| Gene Symbol | wbp1 |
|---|---|
| Entrez Gene | 2539520 |
| Alt Symbol | - |
| Species | S. pombe |
| Gene Type | protein-coding |
| Description | dolichyl-di-phosphooligosaccharide-protein glycotransferase subunit Wbp1 (predicted) |
| Other Description | - |
| Swissprots | Q7LWC1 O59866 |
| Accessions | CAA19346 O59866 NM_001023142 NP_588153 |
| Function | Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER) (By similarity). {ECO:0000250}. |
| Subcellular Location | Endoplasmic reticulum {ECO:0000269|PubMed:16823372}. Membrane {ECO:0000250|UniProtKB:P33767}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P33767}. |
| Top Pathways | N-Glycan biosynthesis, Protein processing in endoplasmic reticulum, Various types of N-glycan biosynthesis |