Gene Symbol | YWHAG |
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Entrez Gene | 7532 |
Alt Symbol | 14-3-3GAMMA, PPP1R170 |
Species | Human |
Gene Type | protein-coding |
Description | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma |
Other Description | 14-3-3 gamma|14-3-3 protein gamma|KCIP-1|protein kinase C inhibitor protein 1|protein phosphatase 1, regulatory subunit 170|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide |
Swissprots | P61981 Q6FH52 |
Accessions | EAW71804 P61981 AB024334 BAA85184 AF142498 AAD48408 AK024230 BAG51276 AK293505 BAG56989 AK295029 BAG58085 BC020963 AAH20963 BI495132 CR541904 CAG46702 CR541925 CAG46723 DC343104 NM_012479 NP_036611 |
Function | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. {ECO:0000269|PubMed:16511572}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Highly expressed in brain, skeletal muscle, and heart. {ECO:0000269|PubMed:10486217}. |
Top Pathways | Cell cycle, Oocyte meiosis, Viral carcinogenesis, PI3K-Akt signaling pathway, Epstein-Barr virus infection |
14-3-3 γ CRISPR/Cas9 KO Plasmid (h) - sc-401063 from Santa Cruz Biotechnology
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14-3-3 γ HDR Plasmid (h) - sc-401063-HDR from Santa Cruz Biotechnology
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14-3-3 γ Double Nickase Plasmid (h) - sc-401063-NIC from Santa Cruz Biotechnology
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14-3-3 γ Double Nickase Plasmid (h2) - sc-401063-NIC-2 from Santa Cruz Biotechnology
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14-3-3 γ CRISPR Activation Plasmid (h) - sc-401063-ACT from Santa Cruz Biotechnology
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14-3-3 γ CRISPR Activation Plasmid (h2) - sc-401063-ACT-2 from Santa Cruz Biotechnology
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14-3-3 γ Lentiviral Activation Particles (h) - sc-401063-LAC from Santa Cruz Biotechnology
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14-3-3 γ Lentiviral Activation Particles (h2) - sc-401063-LAC-2 from Santa Cruz Biotechnology
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14-3-3 γ siRNA (h) - sc-29582 from Santa Cruz Biotechnology
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14-3-3 γ shRNA Plasmid (h) - sc-29582-SH from Santa Cruz Biotechnology
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14-3-3 γ shRNA (h) Lentiviral Particles - sc-29582-V from Santa Cruz Biotechnology
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14-3-3 γ siRNA (h2) - sc-44279 from Santa Cruz Biotechnology
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14-3-3 γ shRNA Plasmid (h2) - sc-44279-SH from Santa Cruz Biotechnology
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14-3-3 γ shRNA (h2) Lentiviral Particles - sc-44279-V from Santa Cruz Biotechnology
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14-3-3 gamma RNAi - H00007532-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN23032 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23032 from Sigma-Aldrich
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YWHAG siRNA (Human) - CRH5145 from Cohesion Biosciences
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YWHAG - MBS8239890 from MyBioSource
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Human YWHAG siRNA - orb265647 from Biorbyt
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YWHAG shRNA Plasmid (Human) - CHH5145 from Cohesion Biosciences
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