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GRM7 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q14831 |
|---|---|
| Clone Names | 100427193 |
| Gene ID | 2917 |
|---|---|
| Other Names | Metabotropic glutamate receptor 7, mGluR7, GRM7, GPRC1G, MGLUR7 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GRM7 |
|---|---|
| Synonyms | GPRC1G, MGLUR7 |
| Function | G-protein coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development (PubMed:33500274). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide- binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase that it inhibits (PubMed:9473604). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum. Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4. |
Research Areas
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$ 277.78
Cat# BP16975a
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