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MEK1 Peptide

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Summary
Product Discontinued
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Order Details


    • Catalog Number
      P2946
    • Availability
      Product Discontinued

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MEK1 Peptide Summary

Immunogen
This protein is not active and should not be used for experiments requiring activity.
Protein/Peptide Type
Peptide
Gene
MAP2K1

Applications/Dilutions

Dilutions
  • Block/Neutralize
Application Notes
This peptide is useful as a blocking peptide for PAB3172.
This product may contain endotoxins and is not suitable for use with live cells.

For further blocking peptide related protocol, click here.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Lyophilized with 100% acetonitrile. Reconstitute with 100 uL deionized water for a final concentration of 1 mg/mL.
Preservative
No Preservative

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MEK1 Peptide

  • dual specificity mitogen-activated protein kinase kinase 1
  • ERK activator kinase 1
  • MAP kinase kinase 1
  • MAP2K1
  • MAPK/ERK kinase 1
  • MAPKK1
  • MEK1
  • MEK1MAPKK 1
  • mitogen-activated protein kinase kinase 1
  • MKK1
  • MKK1MEK 1
  • PRKMK1EC 2.7.12.2
  • protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1)

Background

MEK 1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003). This pathway also plays a key role in synaptic plasticity in brain (Adams and Sweatt, 2002). Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992) Conversely there also appears to be a feedback phosphorylation of MEK 1 by MAP kinase. The sites on MEK 1 that are phosphorylated by MAP kinase are Thr292 and Thr386 (Mansour et al., 1994).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Contact Information

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Bioinformatics

Gene Symbol MAP2K1