SENP6 Peptide

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Summary
Product Discontinued
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Order Details


    • Catalog Number
      P0304
    • Availability
      Product Discontinued

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SENP6 Peptide Summary

Immunogen
This protein is not active and should not be used for experiments requiring activity.
Protein/Peptide Type
Peptide
Gene
SENP6

Applications/Dilutions

Dilutions
  • Block/Neutralize
Application Notes
This peptide is useful as a blocking peptide for PAB1849.
This product may contain endotoxins and is not suitable for use with live cells.

For further blocking peptide related protocol, click here.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Lyophilized with 100% acetonitrile. Reconstitute with 100 uL deionized water for a final concentration of 1 mg/mL.
Preservative
No Preservative

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SENP6 Peptide

  • EC 3.4.22.-
  • KIAA0797FLJ11887
  • Sentrin/SUMO-specific protease SENP6
  • sentrin-specific protease 6
  • SSP1KIAA0389
  • SUMO1/sentrin specific peptidase 6,2810017C20Rik
  • SUMO1/sentrin specific protease 6
  • SUMO-1-specific protease 1
  • SUSP1FLJ11355

Background

Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000 [PubMed 10799485]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol SENP6