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Recombinant Human KMT1A/SUV39H1 GST (N-Term) Protein

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SDS-Page: Recombinant Human KMT1A/SUV39H1 Protein [H00006839-P01] - 12.5% SDS-PAGE Stained with Coomassie Blue.
SDS-Page: Recombinant Human KMT1A/SUV39H1 Protein [H00006839-P01] - 12.5% SDS-PAGE Stained with Coomassie Blue.

Product Details

Summary
Product Discontinued
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    • Catalog Number
      H00006839-P01
    • Availability
      Product Discontinued

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Recombinant Human KMT1A/SUV39H1 GST (N-Term) Protein Summary

Description
A recombinant protein with GST tag at N-terminal corresponding to the amino acids 1-412 of Human SUV39H1

Source: Wheat Germ (in vitro)

Amino Acid Sequence: MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF
Preparation
Method
in vitro wheat germ expression system
Details of Functionality
This protein was produced in an in vitro wheat germ expression system that should preserve correct conformational folding that is necessary for biological function. While it is possible that this protein could display some level of activity, the functionality of this protein has not been explicitly measured or validated.
Source
Wheat germ
Protein/Peptide Type
Recombinant Protein
Gene
SUV39H1
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Dilutions
  • ELISA
  • Immunoaffinity Purification
  • Protein Array
  • SDS-Page
  • Western Blot
Theoretical MW
74.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Preservative
No Preservative
Purity
>80% by SDS-PAGE and Coomassie blue staining

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human KMT1A/SUV39H1 GST (N-Term) Protein

  • EC 2.1.1.355
  • H3-K9-HMTase 1
  • Histone H3-K9 methyltransferase 1
  • histone-lysine N-methyltransferase SUV39H1
  • histone-lysine N-methyltransferase, H3 lysine-9 specific 1
  • KMT1A
  • KMT1A/SUV39H1
  • KMT1AEC 2.1.1.43
  • Lysine N-methyltransferase 1A
  • MG44
  • Position-effect variegation 3-9 homolog
  • Su(var)3-9 homolog 1
  • suppressor of variegation 3-9 (Drosophila) homolog 1
  • suppressor of variegation 3-9 homolog 1 (Drosophila)
  • Suppressor of variegation 3-9 homolog 1
  • Suppressor of variegation 3-9 homolog 1, Suvar) 3-9 homolog
  • SUV39H
  • SUV39H1

Background

This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol SUV39H1