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YSK Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O00506 |
|---|---|
| Clone Names | 2032701 |
| Gene ID | 10494 |
|---|---|
| Other Names | Serine/threonine-protein kinase 25, Ste20-like kinase, Sterile 20/oxidant stress-response kinase 1, SOK-1, Ste20/oxidant stress response kinase 1, STK25, SOK1, YSK1 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7956a was selected from the C-term region of human YSK . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | STK25 (HGNC:11404) |
|---|---|
| Synonyms | SOK1, YSK1 |
| Function | Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration. Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation (PubMed:18782753). |
| Cellular Location | Cytoplasm. Golgi apparatus. Note=Localizes to the Golgi apparatus |
| Tissue Location | Ubiquitously expressed. Highest levels are found in testis, large intestine, brain and stomach followed by heart and lung |
Research Areas
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$ 277.78
Cat# BP7956a
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