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NOMO1 Antibody (S1205) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q15155 |
|---|---|
| Clone Names | 80130104 |
| Gene ID | 23420 |
|---|---|
| Other Names | Nodal modulator 1, pM5 protein, NOMO1, PM5 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7596d was selected from the S1205 region of human NOMO1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NOMO1 |
|---|---|
| Synonyms | PM5 |
| Function | Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes (PubMed:32820719, PubMed:36261522). The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (PubMed:36261522). |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in colon tumor tissue and in adjacent normal colonic mucosa. |
Research Areas
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$ 277.78
Cat# BP7596d
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