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Topo III beta 293T Cell Transient Overexpression Lysate

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Summary
Product Discontinued
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    • Catalog Number
      H00008940-T02
    • Availability
      Product Discontinued

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Topo III beta 293T Cell Transient Overexpression Lysate Summary

Description
Quality control test: Transient overexpression cell lysate was tested with Anti-TOP3B antibody by Western Blots. Plasmid: pCMV-TOP3B full-length
Specificity
Topo III beta 293T Cell Transient Overexpression Lysate(Denatured)
Gene
TOP3B

Applications/Dilutions

Dilutions
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)

Lysate Details for Array

Type
293T Cell Transient Overexpression
Protein State
Denatured

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Topo III beta 293T Cell Transient Overexpression Lysate

  • DNA topoisomerase 3-beta-1
  • DNA topoisomerase III beta-1
  • EC 5.99.1.2
  • FLJ39376
  • TOP3B1
  • topoisomerase (DNA) III beta
  • topoisomerase III beta

Background

Topo III beta encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol TOP3B