Cdk6 Antibody (H-11): sc-271364
- Cdk6 Antibody (H-11) is a mouse monoclonal IgG3 κ, cited in 6 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 291-326 at the C-terminus of Cdk6 of human origin
- recommended for detection of Cdk6 of human origin by WB, IP, IF and ELISA
- See Cdk6 (DCS-83): sc-53638 for Cdk6 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG3 BP-HRP is the preferred secondary detection reagent for Cdk6 Antibody (H-11) for WB applications. This reagent is now offered in a bundle with Cdk6 Antibody (H-11) (see ordering information below).
Cdk6 Antibody (H-11) is a mouse monoclonal IgG3 antibody that detects Cdk6 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Cdk6 is a crucial member of the cyclin-dependent kinase (Cdk) family, which plays a vital role in regulating the cell cycle, particularly during the G1/S transition. anti-Cdk6 antibody (H-11) targets a protein primarily located in the nucleus, where Cdk6 associates with cyclins D1, D2, and D3 to phosphorylate target substrates that drive cell cycle progression. Proper functioning of Cdk6 is essential for cellular proliferation, and dysregulation of its activity can lead to uncontrolled cell division, contributing to cancer development. Additionally, Cdk6 is subject to regulation by specific inhibitors, such as p18 and p19, which can bind to both free and cyclin-bound forms of Cdk6, thereby modulating its activity and ensuring that cell cycle progression occurs in a controlled manner. Cdk6 (H-11) antibody serves as an invaluable tool for researchers studying cell cycle dynamics and the molecular mechanisms underlying cell proliferation and cancer.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cdk6 Antibody (H-11) | sc-271364 | 200 µg/ml | $316.00 | |||
Cdk6 Antibody (H-11): m-IgG3 BP-HRP Bundle | sc-550404 | 200 µg Ab; 40 µg BP | $354.00 | |||
Cdk6 (H-11) Neutralizing Peptide | sc-271364 P | 100 µg/0.5 ml | $68.00 |