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PUMA Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of PUMA Antibodies for advanced research in apoptosis and cell survival mechanisms. PUMA Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PUMA (p53 upregulated modulator of apoptosis) plays a critical role in the apoptotic pathway, acting as a pro-apoptotic member of the Bcl-2 family. PUMA is essential for mediating cell death in response to stress signals and is implicated in various diseases, including cancer. Understanding PUMA function is crucial for developing therapeutic strategies aimed at modulating apoptosis in diseased cells. Researchers can explore PUMA's role in various cellular processes through detailed molecular analysis. Current studies focus on how PUMA influences cell death pathways in different tissue types and disease states. Investigating PUMA's interactions with other proteins provides valuable information about cellular survival mechanisms. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing our understanding of apoptotic pathways and their impact on human health.

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PUMA Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PUMAα Antibody (B-6)

sc-377015mouse IgG1 κ2-29 (h)WB, IP, IF, IHC(P), ELISAm, r, h
27
(9)

PUMAα/β Antibody (G-3)

sc-374223mouse IgG2b κ57-193 (h)WB, IP, IF, ELISAm, r, h
73
(27)

PUMA CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PUMA CRISPR/Cas9 KO Plasmid (m)

sc-431320mGene KnockoutGFP0
(0)

PUMA HDR Plasmid (m)

sc-431320-HDRmHomology Directed RepairPuromycin0
(0)

PUMA Double Nickase Plasmid (m)

sc-431320-NICmGene KnockoutPuromycin0
(0)

PUMA Double Nickase Plasmid (m2)

sc-431320-NIC-2mGene KnockoutPuromycin0
(0)

PUMAα/β Double Nickase Plasmid (h)

sc-400464-NIChGene KnockoutPuromycin
1
(0)

PUMAα/β Double Nickase Plasmid (h2)

sc-400464-NIC-2hGene KnockoutPuromycin
1
(0)

PUMA CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PUMA CRISPR Activation Plasmid (m)

sc-431320-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PUMA CRISPR Activation Plasmid (m2)

sc-431320-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PUMA Lentiviral Activation Particles (m)

sc-431320-LACmGene ActivationPuro, Blast, Hygro0
(0)

PUMA Lentiviral Activation Particles (m2)

sc-431320-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PUMAα/β CRISPR Activation Plasmid (h)

sc-400464-ACThGene ActivationPuro, Blast, Hygro
1
(0)

PUMAα/β CRISPR Activation Plasmid (h2)

sc-400464-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

PUMAα/β Lentiviral Activation Particles (h)

sc-400464-LAChGene ActivationPuro, Blast, Hygro
1
(0)

PUMAα/β Lentiviral Activation Particles (h2)

sc-400464-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

PUMA siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PUMA siRNA (h)

sc-37153hGene SilencingN/A
31
(0)

PUMA siRNA (m)

sc-37154mGene SilencingN/A
1
(0)

PUMA siRNA (r)

sc-270040rGene SilencingN/A
3
(0)

PUMA shRNA Plasmid (r)

sc-270040-SHrGene SilencingPuromycin
3
(0)

PUMA shRNA (r) Lentiviral Particles

sc-270040-VrGene SilencingPuromycin
3
(0)

PUMAα shRNA Plasmid (h)

sc-37153-SHhGene SilencingPuromycin
31
(0)

PUMAα shRNA (h) Lentiviral Particles

sc-37153-VhGene SilencingPuromycin
31
(0)

PUMAα shRNA Plasmid (m)

sc-37154-SHmGene SilencingPuromycin
1
(0)

PUMAα shRNA (m) Lentiviral Particles

sc-37154-VmGene SilencingPuromycin
1
(0)