Troponin C slow skeletal/cardiac Antibody (12G3): sc-52263
- Troponin C slow skeletal/cardiac Antibody (12G3) is a mouse monoclonal IgG2b provided at 100 µg/ml
- raised against human cardiac Troponin C
- recommended for detection of Troponin C slow skeletal/cardiac of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Troponin C slow skeletal/cardiac Antibody (12G3). This work is in progress.
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SEE ALSO...
Troponin C slow skeletal/cardiac Antibody (12G3) is a mouse monoclonal IgG2b antibody that detects Troponin C in human samples through western blotting (WB) and immunoprecipitation (IP) applications. Troponin C plays a critical role in muscle contraction by serving as a calcium sensor, which is essential for the regulation of muscle contraction and relaxation. Troponin C slow skeletal/cardiac (12G3) antibody targets a component of the troponin complex, which also includes Troponin I and Troponin T, and is located on the thin filaments of striated muscle. The ability of Troponin C to bind calcium ions is vital, as it induces conformational changes that allow for the interaction between actin and myosin, ultimately leading to muscle contraction. Notably, Troponin C exists in two isoforms: fast and slow, with the slow/cardiac isoform having a single calcium binding site compared to the two binding sites of the fast isoform. This difference in calcium binding capacity influences the contractile properties of different muscle types, making Troponin C a key player in cardiac and skeletal muscle function. Anti-Troponin C antibody (12G3) serves as an invaluable tool for researchers studying muscle physiology and pathophysiology, particularly in the context of cardiac health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Troponin C slow skeletal/cardiac Antibody (12G3) | sc-52263 | 100 µg/ml | $316.00 |