FAS-L Antibody (1.BB.37): sc-71096

FAS-L Antibody (1.BB.37) is a hamster monoclonal IgG antibody that detects FAS-L in human samples through applications such as immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). FAS-L, or FAS ligand, plays a crucial role in the regulation of apoptosis, particularly in the immune system, where FAS-L mediates the interaction between cytotoxic T lymphocytes and target cells. This interaction is vital for the elimination of virus-infected or transformed cells, as FAS-L binds to its receptor, FAS, triggering a cascade of events that lead to programmed cell death. The ability of FAS-L to induce apoptosis is essential for maintaining immune homeostasis and preventing autoimmune responses, as FAS-L helps to eliminate activated lymphocytes after an immune response has been resolved. Furthermore, the expression of FAS-L on activated T cells allows for the targeted killing of cells that express FAS, thereby ensuring that only those cells that pose a threat to the organism are eliminated. FAS-L (1.BB.37) antibody is an invaluable tool for researchers studying the mechanisms of immune regulation and the pathways involved in cell death, providing insights into potential therapeutic targets for diseases characterized by dysregulated apoptosis.

The preferred FAS-L antibody is FAS-L Antibody (NOK-1): sc-19681.