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Cytokeratin 7/13/17/18 Antibody (LdS 23) is a mouse monoclonal IgG1 kappa light chain antibody engineered to detect multiple members of the Cytokeratin family, including Cytokeratin 7 (KRT7), Cytokeratin 13 (KRT13), Cytokeratin 17 (KRT17), and Cytokeratin 18 (KRT18). Raised against cytoskeleton preparations from the human urothelial RT4 cell line, anti-Cytokeratin 7/13/17/18 antibody (LdS 23) exhibits strong reactivity with human Cytokeratins 7, 13, 17, and 18, making this product ideal for applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Cytokeratins are essential intermediate filament proteins that provide structural integrity and resilience to epithelial cells, facilitating cellular architecture and tissue stability. Specifically, Cytokeratin 7 interacts with Cytokeratin 8 to form stable filaments, while Cytokeratin 13 pairs with Cytokeratin 4, and Cytokeratin 17 associates with Cytokeratin 5, playing critical roles in epithelial differentiation and repair processes. Cytokeratin 18 partners with Cytokeratin 8 to support cellular structure and dynamics, and these interactions are vital for maintaining epithelial cell function and integrity. Cytokeratin 7/13/17/18 (LdS 23) antibody′s ability to simultaneously detect these cytokeratins allows researchers to study complex protein interactions and the intricate network of the cytoskeleton in epithelial biology. This multiplex detection is particularly important for investigating molecular mechanisms underlying epithelial differentiation, tissue specialization, and the pathogenesis of various epithelial-derived cancers. Anti-Cytokeratin 7/13/17/18 antibody (LdS 23) provides comprehensive insights into epithelial cell architecture and pathology, enhancing diagnostic accuracy and facilitating advanced research in cell biology, pathology, and oncology.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytokeratin 7/13/17/18 Antibody (LdS 23) | sc-53265 | 200 µg/ml | $316.00 | |||
Cytokeratin 7/13/17/18 Antibody (LdS 23): m-IgG Fc BP-HRP Bundle | sc-536921 | 200 µg Ab; 10 µg BP | $354.00 | |||
Cytokeratin 7/13/17/18 Antibody (LdS 23): m-IgGκ BP-HRP Bundle | sc-534096 | 200 µg Ab; 40 µg BP | $354.00 | |||
Cytokeratin 7/13/17/18 Antibody (LdS 23): m-IgG1 BP-HRP Bundle | sc-544901 | 200 µg Ab; 20 µg BP | $354.00 |