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ALB Antibody (1G2) is a mouse monoclonal IgG1 kappa light chain antibody designed to recognize full-length purified human albumin (ALB), also known as human serum albumin (HSA). ALB mouse monoclonal antibody (1G2) is validated for use in western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA) applications across mouse, rat, and human species. Albumin is the most abundant protein in blood plasma, synthesized in the liver where processing occurs in the rough endoplasmic reticulum and Golgi apparatus before secretion into the bloodstream. The primary function of albumin is to maintain the colloidal osmotic pressure of blood, which is essential for regulating fluid balance between blood vessels and tissues. Additionally, albumin acts as a carrier protein, binding and transporting various ligands including water, fatty acids, calcium, sodium, bilirubin, hormones, potassium, and numerous drugs, thereby facilitating their distribution and availability throughout the body. The precise localization and processing of albumin within liver cells are crucial for stability and functionality, ensuring efficient transport and regulatory roles. Mutations in the ALB gene can lead to conditions such as familial dysalbuminemic hyperthyroxinemia (FDH), underscoring the clinical importance of albumin in endocrine regulation. ALB monoclonal antibody (1G2) supports researchers in investigating albumin-related physiological processes and disease mechanisms.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ALB/Albumin Antibody (1G2) | sc-58688 | 100 µl | $316.00 |