ALB/Albumin Antibody (E-11): sc-271604
- ALB/Albumin Antibody (E-11) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
- raised against amino acids 39-164 mapping near the N-terminus of serum albumin of human origin
- ALB/Albumin Antibody (E-11) is recommended for detection of ALB of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-ALB/Albumin Antibody (E-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of ALB/Albumin (E-11): sc-271604.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ALB/Albumin Antibody (E-11) for WB and IHC(P) applications. These reagents are now offered in bundles with ALB/Albumin Antibody (E-11) (see ordering information below).
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ALB Antibody (E-11) is a mouse monoclonal IgG1 kappa light chain antibody developed to recognize amino acids 39-164 near the N-terminus of human serum albumin (ALB), also known as human serum albumin (HSA). Anti-ALB antibody (E-11) is validated for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA) applications specifically in human samples. Serum albumin is the most abundant protein in plasma, synthesized in the liver, and plays a critical role in maintaining the colloidal osmotic pressure of blood, which is essential for regulating fluid balance between blood vessels and tissues. Structurally, albumin consists of a single polypeptide chain with multiple binding sites that facilitate the transport of a wide range of ligands, including fatty acids, hormones, bilirubin, and various drugs. Albumin interacts with several key proteins such as fatty acid-binding proteins (FABPs) and the neonatal Fc receptor (FcRn), which are important for the transport and recycling of fatty acids and maintaining albumin′s long half-life in circulation, respectively. These interactions are vital for the efficient distribution and availability of essential molecules throughout the body, underscoring albumin′s role in metabolic regulation and homeostasis. Additionally, albumin binds to and modulates the activity of hormones like thyroxine and various drug molecules, impacting their bioavailability and pharmacokinetics. Post-translational modifications of albumin, including glycation and oxidation, further influence its binding properties and interactions with other proteins, ensuring functionality under diverse physiological conditions. Mutations in the ALB gene can lead to disorders such as familial dysalbuminemic hyperthyroxinemia (FDH), which affects thyroid hormone binding and highlights the clinical significance of albumin interactions. ALB monoclonal antibody (E-11) supports researchers in investigating albumin-related physiological processes and disease mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ALB/Albumin Antibody (E-11) | sc-271604 | 200 µg/ml | $316.00 | |||
ALB/Albumin Antibody (E-11): m-IgG Fc BP-HRP Bundle | sc-527263 | 200 µg Ab; 10 µg BP | $354.00 | |||
ALB/Albumin Antibody (E-11): m-IgG1 BP-HRP Bundle | sc-532636 | 200 µg Ab; 20 µg BP | $354.00 | |||
ALB/Albumin Antibody (E-11) AC | sc-271604 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ALB/Albumin Antibody (E-11) HRP | sc-271604 HRP | 200 µg/ml | $316.00 | |||
ALB/Albumin Antibody (E-11) FITC | sc-271604 FITC | 200 µg/ml | $330.00 | |||
ALB/Albumin Antibody (E-11) PE | sc-271604 PE | 200 µg/ml | $343.00 | |||
ALB/Albumin Antibody (E-11) Alexa Fluor® 488 | sc-271604 AF488 | 200 µg/ml | $357.00 | |||
ALB/Albumin Antibody (E-11) Alexa Fluor® 546 | sc-271604 AF546 | 200 µg/ml | $357.00 | |||
ALB/Albumin Antibody (E-11) Alexa Fluor® 594 | sc-271604 AF594 | 200 µg/ml | $357.00 | |||
ALB/Albumin Antibody (E-11) Alexa Fluor® 647 | sc-271604 AF647 | 200 µg/ml | $357.00 | |||
ALB/Albumin Antibody (E-11) Alexa Fluor® 680 | sc-271604 AF680 | 200 µg/ml | $357.00 | |||
ALB/Albumin Antibody (E-11) Alexa Fluor® 790 | sc-271604 AF790 | 200 µg/ml | $357.00 |