Integrin αL/M/X/β2 Antibody (24): sc-53359
- Integrin αL/M/X/β2 Antibody (24) is a mouse monoclonal IgG1 κ Integrin αL/M/X/β2 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against fibronectin-purified monocytes of human origin
- Integrin alpha L/M/X/ beta 2 Antibody (24) is recommended for detection of a Mg2+ dependent epitope common to all three Integrin α subunits of human origin by IP and FCM
- Integrin alpha L/M/X/ beta 2 Antibody (24) is available conjugated to agarose (sc-53359 AC), 500 µg/ml, 25% agarose, for IP; and to either phycoerythrin (sc-53359 PE), FITC (sc-53359 FITC), Alexa Fluor® 488 (sc-53359 AF488) or Alexa Fluor® 647 (sc-53359 AF647), 200 µg/ml, for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Integrin αL/M/X/β2 (24): sc-53359.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Integrin αL/M/X/β2 Antibody (24) for WB and IHC(P) applications. These reagents are now offered in bundles with Integrin αL/M/X/β2 Antibody (24) (see ordering information below).
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Integrin αL/M/X/β2 Antibody (24) is a mouse monoclonal IgG1 kappa light chain antibody that detects Integrin αL/M/X/β2 protein of human origin by immunoprecipitation (IP) and flow cytometry (FCM). Anti-Integrin αL/M/X/β2 antibody (24) is available in both non-conjugated and various conjugated forms, including agarose, phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Integrin αL/M/X/β2 (24) antibody recognizes a protein that plays a crucial role in immune response by facilitating leukocyte adhesion to endothelial cells, essential for immune cell migration to inflammation or injury sites. This process enables immune cells to exit bloodstream and infiltrate tissues where they combat pathogens or repair damage. Integrin αL/M/X/β2 functions as a heterodimer, composed of alpha and beta subunits, forming a receptor that binds to various ligands, including intracellular adhesion molecules (ICAMs). Anti-Integrin αL/M/X/β2 antibody (24) helps researchers study immune cell trafficking mechanisms and explore implications for inflammatory diseases and therapeutic interventions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Integrin αL/M/X/β2 Antibody (24) References:
- Paxillin binding to the alpha 4 integrin subunit stimulates LFA-1 (integrin alpha L beta 2)-dependent T cell migration by augmenting the activation of focal adhesion kinase/proline-rich tyrosine kinase-2. | Rose, DM., et al. 2003. J Immunol. 170: 5912-8. PMID: 12794117
- The integrin alpha L beta 2 hybrid domain serves as a link for the propagation of activation signal from its stalk regions to the I-like domain. | Tng, E., et al. 2004. J Biol Chem. 279: 54334-9. PMID: 15456774
- Integrins: versatility, modulation, and signaling in cell adhesion. | Hynes, RO. 1992. Cell. 69: 11-25. PMID: 1555235
- The primacy of affinity over clustering in regulation of adhesiveness of the integrin {alpha}L{beta}2. | Kim, M., et al. 2004. J Cell Biol. 167: 1241-53. PMID: 15611342
- Integrins and signal transduction pathways: the road taken. | Clark, EA. and Brugge, JS. 1995. Science. 268: 233-9. PMID: 7716514
- Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. | Miyamoto, S., et al. 1995. Science. 267: 883-5. PMID: 7846531
- Epithelial integrins. | Sheppard, D. 1996. Bioessays. 18: 655-60. PMID: 8760339
- Cooperation between soluble factors and integrin-mediated cell anchorage in the control of cell growth and differentiation. | Juliano, R. 1996. Bioessays. 18: 911-7. PMID: 8939069
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Integrin αL/M/X/β2 Antibody (24) | sc-53359 | 200 µg/ml | $316.00 | |||
Integrin αL/M/X/β2 Antibody (24): m-IgG Fc BP-HRP Bundle | sc-526800 | 200 µg Ab; 10 µg BP | $354.00 | |||
Integrin αL/M/X/β2 Antibody (24): m-IgG1 BP-HRP Bundle | sc-532173 | 200 µg Ab; 20 µg BP | $354.00 | |||
Integrin αL/M/X/β2 Antibody (24) AC | sc-53359 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Integrin αL/M/X/β2 Antibody (24) FITC | sc-53359 FITC | 200 µg/ml | $330.00 | |||
Integrin αL/M/X/β2 Antibody (24) PE | sc-53359 PE | 200 µg/ml | $343.00 | |||
Integrin αL/M/X/β2 Antibody (24) Alexa Fluor® 488 | sc-53359 AF488 | 200 µg/ml | $357.00 | |||
Integrin αL/M/X/β2 Antibody (24) Alexa Fluor® 546 | sc-53359 AF546 | 200 µg/ml | $357.00 | |||
Integrin αL/M/X/β2 Antibody (24) Alexa Fluor® 594 | sc-53359 AF594 | 200 µg/ml | $357.00 | |||
Integrin αL/M/X/β2 Antibody (24) Alexa Fluor® 647 | sc-53359 AF647 | 200 µg/ml | $357.00 | |||
Integrin αL/M/X/β2 Antibody (24) Alexa Fluor® 680 | sc-53359 AF680 | 200 µg/ml | $357.00 | |||
Integrin αL/M/X/β2 Antibody (24) Alexa Fluor® 790 | sc-53359 AF790 | 200 µg/ml | $357.00 |