E-cadherin Antibody (5F133): sc-71007
- E-cadherin Antibody (5F133) is a mouse monoclonal IgG1, cited in 27 publications, provided at 50 µg/0.5 ml
- raised against affinity purified 80 kDa extracellular fragments of E-cadherin of A-431 vulva carcinoma cells of human origin
- recommended for detection of E-Cadherin of mouse, rat and human origin by WB, IP, IF and IHC(P)
- See E-cadherin (G-10): sc-8426 for E-cadherin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for E-cadherin Antibody (5F133). This work is in progress.
QUICK LINKS
SEE ALSO...
E-cadherin Antibody (5F133) is a mouse monoclonal IgG1 antibody that detects E-cadherin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. E-cadherin plays a crucial role in maintaining cell-cell adhesion, which is essential for the integrity of epithelial tissues and the overall architecture of organs. E-cadherin is primarily located at the cell membrane, where E-cadherin forms adherens junctions that connect adjacent cells, thereby facilitating communication and structural stability within tissues. E-cadherin′s location at the membrane is vital for processes such as embryonic development, tissue repair, and the prevention of metastasis in cancer. Disruption of E-cadherin expression or function can lead to increased cellular motility and invasiveness, contributing to tumor progression and the spread of cancer cells. E-cadherin′s interaction with cytoplasmic proteins, including β-catenin, further underscores E-cadherin′s significance in signaling pathways that regulate cell behavior and tissue homeostasis. Anti-E-cadherin antibody (5F133) is an invaluable tool for researchers studying these critical biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
E-cadherin Antibody (5F133) | sc-71007 | 50 µg/0.5 ml | $316.00 |