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BRCA Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of BRCA Antibodies for research focused on understanding BRCA1 and BRCA2 in cellular processes. BRCA Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). BRCA1 and BRCA2 maintain genomic stability and are integral to DNA repair mechanisms. Mutations in BRCA genes significantly increase the risk of breast and ovarian cancers, highlighting their importance in cancer research and therapeutic development. Research focusing on BRCA1 and BRCA2 continues to reveal new insights about their roles in DNA damage response pathways. Understanding BRCA gene expression patterns helps identify potential therapeutic targets for cancer treatment. Ongoing studies of BRCA1 and BRCA2 contribute to developing more effective cancer prevention strategies. Current research explores how BRCA mutations affect cellular responses to various cancer treatments. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of BRCA proteins and their impact on cancer biology.

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BRCA Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

BRCA1 Antibody (D-9)

sc-6954mouse IgG2a κ1843-1862 (h)WB, IP, IF, ELISAh
450
(53)

BRCA1 Antibody (C-11)

sc-514797mouse IgG1 κ1564-1863 (h)WB, IP, IF, IHC(P), ELISAh
1
(0)

BRCA1 Antibody (287.17)

sc-135732mouse IgG2b κ(m)WB, IP, IF, IHC(P), ELISAm, r, h
11
(1)

BRCA1 Antibody (GLK-2)

sc-56030mouse IgM κ1839-1863 (h)WB, IP, IF, IHC(P)h
1
(1)

BRCA2 Antibody (3D12)

sc-293185mouse IgG3 κ3319-3418 (h)WB, IP, ELISAh
10
(5)

BRCA2 Antibody (1643CT739.91.87)

sc-517316mouse IgG1 κ251-495 (h)WBh

new

(0)

BRCA2 Antibody (184H2N)

sc-517636mouse IgG1 κ(h)WBh

new

(0)

Phospho-Specific BRCA Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-BRCA1 Antibody (G-4)

sc-166793mouse IgG1 κSer 988 (h)WB, IP, IF, ELISAh
1
(4)

BRCA CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

BRAT1 CRISPR/Cas9 KO Plasmid (h)

sc-415146hGene KnockoutGFP0
(0)

BRAT1 HDR Plasmid (h)

sc-415146-HDRhHomology Directed RepairPuromycin0
(0)

BRAT1 Double Nickase Plasmid (h)

sc-415146-NIChGene KnockoutPuromycin0
(0)

BRAT1 Double Nickase Plasmid (h2)

sc-415146-NIC-2hGene KnockoutPuromycin0
(0)

BRAT1 CRISPR/Cas9 KO Plasmid (m)

sc-433111mGene KnockoutGFP0
(0)

BRAT1 HDR Plasmid (m)

sc-433111-HDRmHomology Directed RepairPuromycin0
(0)

BRAT1 Double Nickase Plasmid (m)

sc-433111-NICmGene KnockoutPuromycin0
(0)

BRAT1 Double Nickase Plasmid (m2)

sc-433111-NIC-2mGene KnockoutPuromycin0
(0)

BRCA1 CRISPR/Cas9 KO Plasmid (h)

sc-400093hGene KnockoutGFP0
(0)

BRCA1 HDR Plasmid (h)

sc-400093-HDRhHomology Directed RepairPuromycin0
(0)

BRCA1 Double Nickase Plasmid (h)

sc-400093-NIChGene KnockoutPuromycin0
(0)

BRCA1 Double Nickase Plasmid (h2)

sc-400093-NIC-2hGene KnockoutPuromycin0
(0)

BRCA1 CRISPR/Cas9 KO Plasmid (m)

sc-419362mGene KnockoutGFP
2
(0)

BRCA1 HDR Plasmid (m)

sc-419362-HDRmHomology Directed RepairPuromycin
2
(0)

BRCA1 Double Nickase Plasmid (m)

sc-419362-NICmGene KnockoutPuromycin
2
(0)

BRCA1 Double Nickase Plasmid (m2)

sc-419362-NIC-2mGene KnockoutPuromycin
2
(0)

BRCA1 CRISPR/Cas9 KO Plasmid (r)

sc-437320rGene KnockoutGFP0
(0)

BRCA1 HDR Plasmid (r)

sc-437320-HDRrHomology Directed RepairPuromycin0
(0)

BRCA1 Double Nickase Plasmid (r)

sc-437320-NICrGene KnockoutPuromycin0
(0)

BRCA1 Double Nickase Plasmid (r2)

sc-437320-NIC-2rGene KnockoutPuromycin0
(0)

BRCA2 CRISPR/Cas9 KO Plasmid (h)

sc-400700hGene KnockoutGFP
4
(0)

BRCA2 HDR Plasmid (h)

sc-400700-HDRhHomology Directed RepairPuromycin
4
(0)

BRCA2 Double Nickase Plasmid (h)

sc-400700-NIChGene KnockoutPuromycin
4
(0)

BRCA2 Double Nickase Plasmid (h2)

sc-400700-NIC-2hGene KnockoutPuromycin
4
(0)

BRCA2 CRISPR/Cas9 KO Plasmid (m)

sc-419363mGene KnockoutGFP0
(0)

BRCA2 HDR Plasmid (m)

sc-419363-HDRmHomology Directed RepairPuromycin0
(0)

BRCA2 Double Nickase Plasmid (m)

sc-419363-NICmGene KnockoutPuromycin0
(0)

BRCA2 Double Nickase Plasmid (m2)

sc-419363-NIC-2mGene KnockoutPuromycin0
(0)

BRCA CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

BRAT1 CRISPR Activation Plasmid (h)

sc-415146-ACThGene ActivationPuro, Blast, Hygro0
(0)

BRAT1 CRISPR Activation Plasmid (h2)

sc-415146-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

BRAT1 Lentiviral Activation Particles (h)

sc-415146-LAChGene ActivationPuro, Blast, Hygro0
(0)

BRAT1 Lentiviral Activation Particles (h2)

sc-415146-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

BRAT1 CRISPR Activation Plasmid (m)

sc-433111-ACTmGene ActivationPuro, Blast, Hygro0
(0)

BRAT1 CRISPR Activation Plasmid (m2)

sc-433111-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

BRAT1 Lentiviral Activation Particles (m)

sc-433111-LACmGene ActivationPuro, Blast, Hygro0
(0)

BRAT1 Lentiviral Activation Particles (m2)

sc-433111-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

BRCA1 CRISPR Activation Plasmid (h)

sc-400093-ACThGene ActivationPuro, Blast, Hygro0
(0)

BRCA1 CRISPR Activation Plasmid (h2)

sc-400093-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

BRCA1 Lentiviral Activation Particles (h)

sc-400093-LAChGene ActivationPuro, Blast, Hygro0
(0)

BRCA1 Lentiviral Activation Particles (h2)

sc-400093-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

BRCA1 CRISPR Activation Plasmid (m)

sc-419362-ACTmGene ActivationPuro, Blast, Hygro
2
(0)

BRCA1 CRISPR Activation Plasmid (m2)

sc-419362-ACT-2mGene ActivationPuro, Blast, Hygro
2
(0)

BRCA1 Lentiviral Activation Particles (m)

sc-419362-LACmGene ActivationPuro, Blast, Hygro
2
(0)

BRCA1 Lentiviral Activation Particles (m2)

sc-419362-LAC-2mGene ActivationPuro, Blast, Hygro
2
(0)

BRCA1 CRISPR Activation Plasmid (r)

sc-437320-ACTrGene ActivationPuro, Blast, Hygro0
(0)

BRCA1 CRISPR Activation Plasmid (r2)

sc-437320-ACT-2rGene ActivationPuro, Blast, Hygro0
(0)

BRCA1 Lentiviral Activation Particles (r)

sc-437320-LACrGene ActivationPuro, Blast, Hygro0
(0)

BRCA1 Lentiviral Activation Particles (r2)

sc-437320-LAC-2rGene ActivationPuro, Blast, Hygro0
(0)

BRCA2 CRISPR Activation Plasmid (h)

sc-400700-ACThGene ActivationPuro, Blast, Hygro
4
(0)

BRCA2 CRISPR Activation Plasmid (h2)

sc-400700-ACT-2hGene ActivationPuro, Blast, Hygro
4
(0)

BRCA2 Lentiviral Activation Particles (h)

sc-400700-LAChGene ActivationPuro, Blast, Hygro
4
(0)

BRCA2 Lentiviral Activation Particles (h2)

sc-400700-LAC-2hGene ActivationPuro, Blast, Hygro
4
(0)

BRCA2 CRISPR Activation Plasmid (m)

sc-419363-ACTmGene ActivationPuro, Blast, Hygro0
(0)

BRCA2 CRISPR Activation Plasmid (m2)

sc-419363-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

BRCA2 Lentiviral Activation Particles (m)

sc-419363-LACmGene ActivationPuro, Blast, Hygro0
(0)

BRCA2 Lentiviral Activation Particles (m2)

sc-419363-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

BRCA siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

BRAT1 siRNA (h)

sc-89333hGene SilencingN/A0
(0)

BRAT1 shRNA Plasmid (h)

sc-89333-SHhGene SilencingPuromycin0
(0)

BRAT1 shRNA (h) Lentiviral Particles

sc-89333-VhGene SilencingPuromycin0
(0)

BRAT1 siRNA (m)

sc-140723mGene SilencingN/A0
(0)

BRAT1 shRNA Plasmid (m)

sc-140723-SHmGene SilencingPuromycin0
(0)

BRAT1 shRNA (m) Lentiviral Particles

sc-140723-VmGene SilencingPuromycin0
(0)

BRCA1 siRNA (h)

sc-29219hGene SilencingN/A
21
(1)

BRCA1 siRNA (h2)

sc-44247hGene SilencingN/A0
(0)

BRCA1 shRNA Plasmid (h)

sc-29219-SHhGene SilencingPuromycin
21
(1)

BRCA1 shRNA Plasmid (h2)

sc-44247-SHhGene SilencingPuromycin0
(0)

BRCA1 shRNA (h) Lentiviral Particles

sc-29219-VhGene SilencingPuromycin
21
(1)

BRCA1 shRNA (h2) Lentiviral Particles

sc-44247-VhGene SilencingPuromycin0
(0)

BRCA1 siRNA (m)

sc-29824mGene SilencingN/A
3
(0)

BRCA1 shRNA Plasmid (m)

sc-29824-SHmGene SilencingPuromycin
3
(0)

BRCA1 shRNA (m) Lentiviral Particles

sc-29824-VmGene SilencingPuromycin
3
(0)

BRCA2 siRNA (h)

sc-29825hGene SilencingN/A
14
(0)

BRCA2 shRNA Plasmid (h)

sc-29825-SHhGene SilencingPuromycin
14
(0)

BRCA2 shRNA (h) Lentiviral Particles

sc-29825-VhGene SilencingPuromycin
14
(0)

BRCA2 siRNA (m)

sc-29826mGene SilencingN/A0
(0)

BRCA2 shRNA Plasmid (m)

sc-29826-SHmGene SilencingPuromycin0
(0)

BRCA2 shRNA (m) Lentiviral Particles

sc-29826-VmGene SilencingPuromycin0
(0)