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CD38 Antibody (T16) is a mouse monoclonal IgG1 antibody that detects CD38 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). CD38 is a type II integral membrane glycoprotein predominantly expressed on early B and T cell lineages, as well as activated B and T cells, while being absent from most mature resting peripheral lymphocytes. CD38 plays a crucial role in immune response regulation, acting as a NAD glycohydrolase that facilitates the activation, proliferation, and differentiation of mature T and B cells. CD38 is involved in the production of calcium-mobilizing metabolites, including cyclic adenosine diphosphate ribose (cADPR), which are essential for various signaling pathways within lymphocytes. CD38 contributes to the survival of invariant natural killer T (iNKT) cells, a subset that is vital for maintaining immunological tolerance. CD38′s dual function as a signaling receptor and enzyme underscores its importance in immune system dynamics, making anti-CD38 antibody (T16) an invaluable tool for researchers studying immune responses and related disorders.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD38 Antibody (T16) | sc-51726 | 100 µg/ml | $316.00 | |||
CD38 Antibody (T16) PE | sc-51726 PE | 100 tests in 2 ml | $343.00 |