Bag-1 Antibody (F-7): sc-25296
- Bag-1 Antibody (F-7) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 73-274 of Bag-1 of human origin
- recommended for detection of Bag-1 of human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Bag-1 Antibody (F-7) for WB and IHC(P) applications. These reagents are now offered in bundles with Bag-1 Antibody (F-7) (see ordering information below).
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Bag-1 Antibody (F-7) is a mouse monoclonal IgG1 antibody that detects Bag-1 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Bag-1 is a critical regulator of apoptosis, functioning as a Bcl-2-binding protein that enhances the protective effects of Bcl-2 against cell death. This interaction suggests Bag-1 may play a pivotal role in determining cell fate under stress conditions, potentially influencing the effectiveness of cancer therapies that target apoptotic pathways. Bag-1 can modulate the balance between survival and apoptosis, making anti-Bag-1 antibody (F-7) significant for studying cancer biology and therapeutic resistance. Using Bag-1 (F-7) monoclonal antibody enables researchers to gain insights into apoptosis regulation and the interplay between Bag-1 and Bcl-2, advancing understanding of cellular responses to various stimuli.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Bag-1 Antibody (F-7) References:
- BAG-1 family of cochaperones in the modulation of nuclear receptor action. | Cato, AC. and Mink, S. 2001. J Steroid Biochem Mol Biol. 78: 379-88. PMID: 11738548
- BAG-1 expression and function in human cancer. | Cutress, RI., et al. 2002. Br J Cancer. 87: 834-9. PMID: 12373595
- BAG-1 in carcinogenesis. | Sharp, A., et al. 2004. Expert Rev Mol Med. 6: 1-15. PMID: 15033003
- Bag-1 proteins in oral squamous cell carcinoma. | Wood, J., et al. 2009. Oral Oncol. 45: 94-102. PMID: 18804403
- BAG-1 as a biomarker in early breast cancer prognosis: a systematic review with meta-analyses. | Papadakis, ES., et al. 2017. Br J Cancer. 116: 1585-1594. PMID: 28510570
- Bag-1 mediates glucocorticoid receptor trafficking to mitochondria after corticosterone stimulation: Potential role in regulating affective resilience. | Luo, S., et al. 2021. J Neurochem. 158: 358-372. PMID: 33025573
- Co-Chaperone Bag-1 Plays a Role in the Autophagy-Dependent Cell Survival through Beclin 1 Interaction. | Turk, M., et al. 2021. Molecules. 26: PMID: 33561998
- CRISPR/Cas9-mediated Bag-1 knockout increased mesenchymal characteristics of MCF-7 cells via Akt hyperactivation-mediated actin cytoskeleton remodeling. | Kilbas, PO., et al. 2022. PLoS One. 17: e0261062. PMID: 34995286
- Bag-1 Protects Nucleus Pulposus Cells from Oxidative Stress by Interacting with HSP70. | Suyama, K., et al. 2023. Biomedicines. 11: PMID: 36979842
- Melatonin, BAG-1 and cortisol circadian interactions in tumor pathogenesis and patterned immune responses. | Anderson, G. 2023. Explor Target Antitumor Ther. 4: 962-993. PMID: 37970210
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bag-1 Antibody (F-7) | sc-25296 | 200 µg/ml | $316.00 | |||
Bag-1 Antibody (F-7): m-IgG Fc BP-HRP Bundle | sc-536703 | 200 µg Ab; 10 µg BP | $354.00 | |||
Bag-1 Antibody (F-7): m-IgGκ BP-HRP Bundle | sc-533863 | 200 µg Ab; 40 µg BP | $354.00 | |||
Bag-1 Antibody (F-7): m-IgG1 BP-HRP Bundle | sc-544773 | 200 µg Ab; 20 µg BP | $354.00 |