Trk Antibodies
Santa Cruz Biotechnology features a diverse variety of Trk monoclonal antibodies for neurobiology and cell signaling research. Trk Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Trk proteins, or tropomyosin receptor kinases, play a crucial role in neuronal development and function by mediating the effects of neurotrophins, which are essential for the survival and differentiation of neurons. The Trk family includes TrkA, TrkB, and TrkC, each involved in distinct signaling pathways that influence processes such as synaptic plasticity and neuroprotection. Understanding Trk protein function is vital for elucidating mechanisms underlying neurodegenerative diseases and developing targeted therapies. Researchers can explore neurotrophin signaling pathways using specific monoclonal antibodies for each Trk family member. Advanced research techniques supported by Santa Cruz Biotechnology monoclonal antibodies enable scientists to make meaningful discoveries in neuroscience and contribute to the development of new therapeutic strategies.
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Trk Antibodies
| Empty Table Header | Product Name | CATALOG # | ISOTYPE | EPITOPE | APPLICATIONS | Species | Citations | RATING |
|---|---|---|---|---|---|---|---|---|
Trk Antibody (B-3) | sc-7268 | mouse IgG2a κ | 783-796 (h) | WB, IP, IF, IHC(P), ELISA | m, r, h | 72 | ||
Trk Antibody (MCTrks) | sc-414 | mouse IgG1 κ | 777-790 (h) | WB, IP, IF, IHC(P) | m, r, h | 12 | ||
Trk Antibody (C-8) | sc-514932 | mouse IgG3 κ | 809-825 (porcine) | WB, IP, IF, ELISA | m, r, h | new | ||
Trk A Antibody (Y32Ex) | sc-80398 | mouse IgG2a κ | (h) | WB | h | 2 | ||
TrkB Antibody (H-8) | sc-136990 | mouse IgG2b κ | 209-298 (h) | WB, IP, IF, ELISA | h | 14 | ||
TrkB Antibody (F-1) | sc-377218 | mouse IgM κ | 37-75 (h) | WB, IP, IF, IHC(P), ELISA | m, r, h | 38 | ||
TrkB Antibody (G-11) | sc-136991 | mouse IgG1 κ | 209-298 (h) | WB, IP, IF, ELISA | h | 1 | ||
Trk C Antibody (7H6) | sc-517245 | mouse IgG1 κ | 32-429 (h) | WB, IP, IF, IHC(P), ELISA | m, r, h | 2 | ||
Trk C Antibody (WW6) | sc-80403 | mouse IgG2b κ | (h) | WB, IF, IHC(P) | h | 3 |
Phospho-Specific Trk Antibodies
| Empty Table Header | Product Name | CATALOG # | ISOTYPE | EPITOPE | APPLICATIONS | Species | Citations | RATING |
|---|---|---|---|---|---|---|---|---|
p-Trk Antibody (E-6) | sc-8058 | mouse IgG1 κ | Tyr 496 (h) | WB, IP, IF, IHC(P), ELISA | m, r, h | 62 |
Non-Mammalian Trk Antibodies
| Empty Table Header | Product Name | CATALOG # | ISOTYPE | EPITOPE | APPLICATIONS | Species | Citations | RATING |
|---|---|---|---|---|---|---|---|---|
TrkA family transport protein Antibody (A-9) | sc-398728 | mouse IgG1 κ | FL (Streptococcus equi subsp. equi 4047) | WB, IP, IF, ELISA | Streptococcus equi subsp. equi 4047 | 1 |
Trk CRISPR Knockout, HDR and Double Nickase Plasmids
| Empty Table Header | Product Name | CATALOG # | Species | APPLICATIONS | MARKER | Citations | RATING |
|---|---|---|---|---|---|---|---|
Trk A CRISPR/Cas9 KO Plasmid (h) | sc-400188 | h | Gene Knockout | GFP | 0 | ||
Trk A HDR Plasmid (h) | sc-400188-HDR | h | Homology Directed Repair | Puromycin | 0 | ||
Trk A Double Nickase Plasmid (h) | sc-400188-NIC | h | Gene Knockout | Puromycin | 0 | ||
Trk A Double Nickase Plasmid (h2) | sc-400188-NIC-2 | h | Gene Knockout | Puromycin | 0 | ||
Trk A CRISPR/Cas9 KO Plasmid (m) | sc-421982 | m | Gene Knockout | GFP | 0 | ||
Trk A HDR Plasmid (m) | sc-421982-HDR | m | Homology Directed Repair | Puromycin | 0 | ||
Trk A Double Nickase Plasmid (m) | sc-421982-NIC | m | Gene Knockout | Puromycin | 0 | ||
Trk A Double Nickase Plasmid (m2) | sc-421982-NIC-2 | m | Gene Knockout | Puromycin | 0 | ||
TrkB CRISPR/Cas9 KO Plasmid (h) | sc-400142 | h | Gene Knockout | GFP | 1 | ||
TrkB HDR Plasmid (h) | sc-400142-HDR | h | Homology Directed Repair | Puromycin | 1 | ||
TrkB Double Nickase Plasmid (h) | sc-400142-NIC | h | Gene Knockout | Puromycin | 1 | ||
TrkB Double Nickase Plasmid (h2) | sc-400142-NIC-2 | h | Gene Knockout | Puromycin | 1 | ||
TrkB CRISPR/Cas9 KO Plasmid (m) | sc-421983 | m | Gene Knockout | GFP | 0 | ||
TrkB HDR Plasmid (m) | sc-421983-HDR | m | Homology Directed Repair | Puromycin | 0 | ||
TrkB Double Nickase Plasmid (m) | sc-421983-NIC | m | Gene Knockout | Puromycin | 0 | ||
TrkB Double Nickase Plasmid (m2) | sc-421983-NIC-2 | m | Gene Knockout | Puromycin | 0 | ||
Trk C CRISPR/Cas9 KO Plasmid (h) | sc-400854 | h | Gene Knockout | GFP | 0 | ||
Trk C HDR Plasmid (h) | sc-400854-HDR | h | Homology Directed Repair | Puromycin | 0 | ||
Trk C Double Nickase Plasmid (h) | sc-400854-NIC | h | Gene Knockout | Puromycin | 0 | ||
Trk C Double Nickase Plasmid (h2) | sc-400854-NIC-2 | h | Gene Knockout | Puromycin | 0 | ||
Trk C CRISPR/Cas9 KO Plasmid (m) | sc-421984 | m | Gene Knockout | GFP | 0 | ||
Trk C HDR Plasmid (m) | sc-421984-HDR | m | Homology Directed Repair | Puromycin | 0 | ||
Trk C Double Nickase Plasmid (m) | sc-421984-NIC | m | Gene Knockout | Puromycin | 0 | ||
Trk C Double Nickase Plasmid (m2) | sc-421984-NIC-2 | m | Gene Knockout | Puromycin | 0 |
Trk CRISPR Activation Products
| Empty Table Header | Product Name | CATALOG # | Species | APPLICATIONS | MARKER | Citations | RATING |
|---|---|---|---|---|---|---|---|
Trk A CRISPR Activation Plasmid (h) | sc-400188-ACT | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
Trk A CRISPR Activation Plasmid (h2) | sc-400188-ACT-2 | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
Trk A Lentiviral Activation Particles (h) | sc-400188-LAC | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
Trk A Lentiviral Activation Particles (h2) | sc-400188-LAC-2 | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
Trk A CRISPR Activation Plasmid (m) | sc-421982-ACT | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
Trk A CRISPR Activation Plasmid (m2) | sc-421982-ACT-2 | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
Trk A Lentiviral Activation Particles (m) | sc-421982-LAC | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
Trk A Lentiviral Activation Particles (m2) | sc-421982-LAC-2 | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
TrkB CRISPR Activation Plasmid (h) | sc-400142-ACT | h | Gene Activation | Puro, Blast, Hygro | 1 | ||
TrkB CRISPR Activation Plasmid (h2) | sc-400142-ACT-2 | h | Gene Activation | Puro, Blast, Hygro | 1 | ||
TrkB Lentiviral Activation Particles (h) | sc-400142-LAC | h | Gene Activation | Puro, Blast, Hygro | 1 | ||
TrkB Lentiviral Activation Particles (h2) | sc-400142-LAC-2 | h | Gene Activation | Puro, Blast, Hygro | 1 | ||
TrkB CRISPR Activation Plasmid (m) | sc-421983-ACT | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
TrkB CRISPR Activation Plasmid (m2) | sc-421983-ACT-2 | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
TrkB Lentiviral Activation Particles (m) | sc-421983-LAC | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
TrkB Lentiviral Activation Particles (m2) | sc-421983-LAC-2 | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
Trk C CRISPR Activation Plasmid (h) | sc-400854-ACT | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
Trk C CRISPR Activation Plasmid (h2) | sc-400854-ACT-2 | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
Trk C Lentiviral Activation Particles (h) | sc-400854-LAC | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
Trk C Lentiviral Activation Particles (h2) | sc-400854-LAC-2 | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
Trk C CRISPR Activation Plasmid (m) | sc-421984-ACT | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
Trk C CRISPR Activation Plasmid (m2) | sc-421984-ACT-2 | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
Trk C Lentiviral Activation Particles (m) | sc-421984-LAC | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
Trk C Lentiviral Activation Particles (m2) | sc-421984-LAC-2 | m | Gene Activation | Puro, Blast, Hygro | 0 |
Trk siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers
| Empty Table Header | Product Name | CATALOG # | Species | APPLICATIONS | MARKER | Citations | RATING |
|---|---|---|---|---|---|---|---|
Trk siRNA (h) | sc-29511 | h | Gene Silencing | N/A | 0 | ||
Trk shRNA Plasmid (h) | sc-29511-SH | h | Gene Silencing | Puromycin | 0 | ||
Trk shRNA (h) Lentiviral Particles | sc-29511-V | h | Gene Silencing | Puromycin | 0 | ||
Trk siRNA (m) | sc-29512 | m | Gene Silencing | N/A | 0 | ||
Trk shRNA Plasmid (m) | sc-29512-SH | m | Gene Silencing | Puromycin | 0 | ||
Trk shRNA (m) Lentiviral Particles | sc-29512-V | m | Gene Silencing | Puromycin | 0 | ||
Trk A siRNA (h) | sc-36726 | h | Gene Silencing | N/A | 4 | ||
Trk A shRNA Plasmid (h) | sc-36726-SH | h | Gene Silencing | Puromycin | 4 | ||
Trk A shRNA (h) Lentiviral Particles | sc-36726-V | h | Gene Silencing | Puromycin | 4 | ||
Trk A siRNA (m) | sc-36727 | m | Gene Silencing | N/A | 1 | ||
Trk A shRNA Plasmid (m) | sc-36727-SH | m | Gene Silencing | Puromycin | 1 | ||
Trk A shRNA (m) Lentiviral Particles | sc-36727-V | m | Gene Silencing | Puromycin | 1 | ||
TrkB siRNA (h) | sc-36728 | h | Gene Silencing | N/A | 3 | ||
TrkB shRNA Plasmid (h) | sc-36728-SH | h | Gene Silencing | Puromycin | 3 | ||
TrkB shRNA (h) Lentiviral Particles | sc-36728-V | h | Gene Silencing | Puromycin | 3 | ||
TrkB siRNA (m) | sc-36729 | m | Gene Silencing | N/A | 1 | ||
TrkB shRNA Plasmid (m) | sc-36729-SH | m | Gene Silencing | Puromycin | 1 | ||
TrkB shRNA (m) Lentiviral Particles | sc-36729-V | m | Gene Silencing | Puromycin | 1 | ||
TrkB siRNA (r) | sc-270466 | r | Gene Silencing | N/A | 3 | ||
TrkB shRNA Plasmid (r) | sc-270466-SH | r | Gene Silencing | Puromycin | 3 | ||
TrkB shRNA (r) Lentiviral Particles | sc-270466-V | r | Gene Silencing | Puromycin | 3 | ||
TrkB siRNA (T. guttata) | sc-270129 | T. guttata | Gene Silencing | N/A | 1 | ||
TrkB shRNA Plasmid (T. guttata) | sc-270129-SH | T. guttata | Gene Silencing | Puromycin | 1 | ||
TrkB shRNA (T. guttata) Lentiviral Particles | sc-270129-V | T. guttata | Gene Silencing | Puromycin | 1 | ||
Trk C siRNA (h) | sc-36730 | h | Gene Silencing | N/A | 0 | ||
Trk C shRNA Plasmid (h) | sc-36730-SH | h | Gene Silencing | Puromycin | 0 | ||
Trk C shRNA (h) Lentiviral Particles | sc-36730-V | h | Gene Silencing | Puromycin | 0 | ||
Trk C siRNA (m) | sc-36731 | m | Gene Silencing | N/A | 0 | ||
Trk C shRNA Plasmid (m) | sc-36731-SH | m | Gene Silencing | Puromycin | 0 | ||
Trk C shRNA (m) Lentiviral Particles | sc-36731-V | m | Gene Silencing | Puromycin | 0 |
Trk Transfected Lysates
| Empty Table Header | Product Name | CATALOG # | Species | CONTROL ANTIBODY | Citations | RATING |
|---|---|---|---|---|---|---|
TrkB (h): 293T Lysate | sc-113925 | h | 3 |