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Gephyrin Antibodies

Santa Cruz Biotechnology features a diverse variety of Gephyrin monoclonal antibodies for research in understanding gephyrin's role in synaptic function and neuronal signaling. Gephyrin monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Gephyrin is a crucial scaffolding protein that plays a significant role in the clustering of inhibitory neurotransmitter receptors at synapses, particularly glycine and GABA receptors. Proper gephyrin function maintains synaptic balance and plasticity, which are vital for normal brain function. Research has shown that gephyrin dysregulation is linked to various neurological disorders, making it an important focus area in neuroscience. Understanding gephyrin's molecular mechanisms can provide insights into potential therapeutic strategies for neurological conditions. Investigating gephyrin's interactions with other synaptic proteins helps reveal the complexity of neural circuit organization. Exploring gephyrin's role in receptor clustering advances knowledge of synaptic transmission and plasticity. Santa Cruz Biotechnology monoclonal antibodies enable researchers to make meaningful contributions to neuroscience and advance our understanding of neurological health and disease.

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Gephyrin Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Gephyrin Antibody (G-6)

sc-25311mouse IgG2b κ437-736 (h)WB, IP, IF, IHC(P), ELISAm, r, h
18
(8)

Gephyrin Antibody (45)

sc-135920mouse IgG1569-726 (r)WB, IP, IF, IHC(P)m, r, h
1
(3)

Gephyrin Antibody (B-4)

sc-55469mouse IgG2b κ437-736 (h)WB, IP, IF, ELISAm, r, h

new

(2)

Gephyrin CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Gephyrin CRISPR/Cas9 KO Plasmid (h)

sc-401197hGene KnockoutGFP0
(0)

Gephyrin HDR Plasmid (h)

sc-401197-HDRhHomology Directed RepairPuromycin0
(0)

Gephyrin Double Nickase Plasmid (h)

sc-401197-NIChGene KnockoutPuromycin0
(0)

Gephyrin Double Nickase Plasmid (h2)

sc-401197-NIC-2hGene KnockoutPuromycin0
(0)

Gephyrin CRISPR/Cas9 KO Plasmid (m)

sc-435262mGene KnockoutGFP0
(0)

Gephyrin HDR Plasmid (m)

sc-435262-HDRmHomology Directed RepairPuromycin0
(0)

Gephyrin Double Nickase Plasmid (m)

sc-435262-NICmGene KnockoutPuromycin0
(0)

Gephyrin Double Nickase Plasmid (m2)

sc-435262-NIC-2mGene KnockoutPuromycin0
(0)

Gephyrin CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Gephyrin CRISPR Activation Plasmid (h)

sc-401197-ACThGene ActivationPuro, Blast, Hygro0
(0)

Gephyrin CRISPR Activation Plasmid (h2)

sc-401197-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Gephyrin Lentiviral Activation Particles (h)

sc-401197-LAChGene ActivationPuro, Blast, Hygro0
(0)

Gephyrin Lentiviral Activation Particles (h2)

sc-401197-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Gephyrin CRISPR Activation Plasmid (m)

sc-435262-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Gephyrin CRISPR Activation Plasmid (m2)

sc-435262-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Gephyrin Lentiviral Activation Particles (m)

sc-435262-LACmGene ActivationPuro, Blast, Hygro0
(0)

Gephyrin Lentiviral Activation Particles (m2)

sc-435262-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Gephyrin siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Gephyrin siRNA (h)

sc-35464hGene SilencingN/A0
(0)

Gephyrin shRNA Plasmid (h)

sc-35464-SHhGene SilencingPuromycin0
(0)

Gephyrin shRNA (h) Lentiviral Particles

sc-35464-VhGene SilencingPuromycin0
(0)

Gephyrin siRNA (m)

sc-35465mGene SilencingN/A0
(0)

Gephyrin shRNA Plasmid (m)

sc-35465-SHmGene SilencingPuromycin0
(0)

Gephyrin shRNA (m) Lentiviral Particles

sc-35465-VmGene SilencingPuromycin0
(0)