TRP2/DCT Antibody (F-7): sc-166766
- TRP2/DCT Antibody (F-7) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 60-90 near the N-terminus of TRP2 of human origin
- recommended for detection of TRP2 of mouse, rat and human origin by WB, IP, IF and ELISA
- See TRP2/DCT (C-9): sc-74439 for TRP2/DCT antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TRP2/DCT Antibody (F-7) for WB applications. These reagents are now offered in bundles with TRP2/DCT Antibody (F-7) (see ordering information below).
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TRP2 Antibody (F-7) is a mouse monoclonal IgG2a antibody that detects TRP2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TRP2, also known as tyrosinase-related protein 2, plays a crucial role in the melanin biosynthesis pathway, specifically in the conversion of DOPA to dopachrome, which is a key step in the production of eumelanin and pheomelanin. TRP2 is primarily located in the melanosomes of melanocytes, where TRP2 collaborates with other enzymes, including tyrosinase and TRP1, to facilitate melanin synthesis. Proper functioning of TRP2 is essential for normal pigmentation; defects in TRP2 activity can lead to pigmentation disorders such as oculocutaneous albinism. The structural integrity of TRP2, which includes a transmembrane domain and metal-binding sites, is vital for enzymatic activity and stability within the melanosomal membrane. Additionally, TRP2 interacts with TRP1 and tyrosinase, forming a multi-enzyme complex that enhances the efficiency of melanin production, underscoring the importance of these proteins in maintaining skin and hair pigmentation. Anti-TRP2 antibody (F-7) is an invaluable tool for researchers studying pigmentation, melanin biosynthesis, and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRP2/DCT Antibody (F-7) | sc-166766 | 200 µg/ml | $316.00 | |||
TRP2/DCT Antibody (F-7): m-IgG Fc BP-HRP Bundle | sc-537528 | 200 µg Ab; 10 µg BP | $354.00 | |||
TRP2/DCT Antibody (F-7): m-IgGκ BP-HRP Bundle | sc-534821 | 200 µg Ab; 40 µg BP | $354.00 | |||
TRP2/DCT Antibody (F-7): m-IgG2a BP-HRP Bundle | sc-548043 | 200 µg Ab; 10 µg BP | $354.00 | |||
TRP2/DCT (F-7) Neutralizing Peptide | sc-166766 P | 100 µg/0.5 ml | $68.00 |