PTBP2 Antibody Summary
Immunogen |
Peptide with sequence C-SKKFKGEDKMD corresponding to internal region according to NP_067013.1 . |
Epitope |
SKKFKGEDKMD |
Localization |
Nuclear |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Goat |
Gene |
PTBP2 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Peptide ELISA Detection limit 1:1000
|
Application Notes |
WB: Preliminary experiments gave an approx. 35 kDa band in lysates of NIH3T3 after 0.1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 57.5 kDa band according to NP_067013.1. The 35 kDa band was successfully blocked by incubation with the immunizing peptide. |
Control |
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Publications |
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Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA |
Preservative |
0.02% Sodium Azide |
Concentration |
0.5 mg/ml |
Purity |
Immunogen affinity purified |
Notes
Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.
Alternate Names for PTBP2 Antibody
Background
PTPBP2 is an RNA-binding protein which binds to intronic polypyrimidine tracts. It binds to the CUCUCU splicing repressor element of the downstream control sequence (DCS) and mediates negative regulation of exons splicing. It may also have a role in the regulation of translation. PTBP2 is thought to be involved in the switch to neuronal specific alternative splicing patterns during neuronal differentiation.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for PTBP2 Antibody (NB100-77333)(1)
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FAQs for PTBP2 Antibody (NB100-77333) (0)
Control Lysate(s)
Secondary Antibodies
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Isotype Controls
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