SOS2 Antibody - BSA Free

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Independent Antibodies: Immunoprecipitation: SOS2 Antibody [NBP1-05958] - Detection of human SOS2 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml
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Independent Antibodies

       
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SOS2 Antibody - BSA Free Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1282 and 1332 of human son of sevenless ortholog 2 using the numbering given in entry NP_008870.2 (GeneID 6655).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SOS2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 2 - 10 ug/mg lysate
  • Western Blot 1:2000-1:10000

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SOS2 Antibody - BSA Free

  • FLJ25596
  • guanine nucleotide exchange factor
  • guanine nucleotide releasing factor
  • son of sevenless (Drosophilia) homolog 2
  • son of sevenless homolog 2 (Drosophila)
  • son of sevenless homolog 2
  • SOS2
  • SOS-2

Background

SOS2 (son of sevenless homolog 2) is a human paralog of the Drosophila SOS gene. Drosophila SOS was originally identified as a gene that functioned downstream of the sevenless gene in the Ras/MAP kinase signaling pathway. SOS and its paralogs, SOS1 and SOS2, function as guanine nucleotide exchange factors that act on Ras-GTPases to cause release of GDP in exchange for GTP. Although targeted disruption of SOS1 results in embryonic lethality, disruption of SOS2 does not have any effects on mouse development, growth, or fertility.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SOS2
Entrez
Uniprot