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DMGDH Antibody (A-9) is a mouse monoclonal IgG2a light chain antibody that detects dimethylglycine dehydrogenase (DMGDH) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DMGDH is an 866 amino acid mitochondrial protein that plays a crucial role in choline catabolism by catalyzing the demethylation of dimethylglycine to form sarcosine, a process vital for maintaining proper metabolic function. DMGDH exists as a monomer and belongs to the gcvT family, utilizing flavin adenine dinucleotide (FAD) and folate as essential cofactors for activity. DMGDH gene is located on human chromosome 5q14.1, and mutations can lead to DMGDH deficiency, a condition characterized by muscle fatigue, a distinctive fish-like odor, and elevated levels of N,N-dimethylglycine in urine. DMGDH′s interaction with other metabolic pathways highlights DMGDH′s importance in cellular metabolism and energy production, making anti-DMGDH antibody (A-9) an invaluable tool for researchers studying metabolic disorders and mitochondrial function.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DMGDH Antibody (A-9) | sc-398256 | 200 µg/ml | $316.00 | |||
DMGDH Antibody (A-9): m-IgG Fc BP-HRP Bundle | sc-538408 | 200 µg Ab; 10 µg BP | $354.00 | |||
DMGDH Antibody (A-9): m-IgGκ BP-HRP Bundle | sc-536017 | 200 µg Ab; 40 µg BP | $354.00 | |||
DMGDH Antibody (A-9): m-IgG2a BP-HRP Bundle | sc-548292 | 200 µg Ab; 10 µg BP | $354.00 |