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DMGDH Antibody (A-9): sc-398256

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Datasheets
  • DMGDH Antibody (A-9) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
  • raised against amino acids 124-271 mapping within an internal region of DMGDH of human origin
  • recommended for detection of DMGDH of mouse, rat and human origin by WB, IP, IF and ELISA
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for DMGDH Antibody (A-9) for WB applications. These reagents are now offered in bundles with DMGDH Antibody (A-9) (see ordering information below).

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    DMGDH Antibody (A-9) is a mouse monoclonal IgG2a light chain antibody that detects dimethylglycine dehydrogenase (DMGDH) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DMGDH is an 866 amino acid mitochondrial protein that plays a crucial role in choline catabolism by catalyzing the demethylation of dimethylglycine to form sarcosine, a process vital for maintaining proper metabolic function. DMGDH exists as a monomer and belongs to the gcvT family, utilizing flavin adenine dinucleotide (FAD) and folate as essential cofactors for activity. DMGDH gene is located on human chromosome 5q14.1, and mutations can lead to DMGDH deficiency, a condition characterized by muscle fatigue, a distinctive fish-like odor, and elevated levels of N,N-dimethylglycine in urine. DMGDH′s interaction with other metabolic pathways highlights DMGDH′s importance in cellular metabolism and energy production, making anti-DMGDH antibody (A-9) an invaluable tool for researchers studying metabolic disorders and mitochondrial function.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    DMGDH Antibody (A-9)

    sc-398256
    200 µg/ml
    $316.00

    DMGDH Antibody (A-9): m-IgG Fc BP-HRP Bundle

    sc-538408
    200 µg Ab; 10 µg BP
    $354.00

    DMGDH Antibody (A-9): m-IgGκ BP-HRP Bundle

    sc-536017
    200 µg Ab; 40 µg BP
    $354.00

    DMGDH Antibody (A-9): m-IgG2a BP-HRP Bundle

    sc-548292
    200 µg Ab; 10 µg BP
    $354.00

    I need to use an antibody to detect the protein in samples of canine origin. Do you know if DMGDH (A-9): sc-398256 mouse monoclonal antibody will work?

    Asked by: Dr Ninau Qelp
    Thank you for your inquiry. Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity. We are available by phone, e-mail or chat.
    Answered by: Technical Support
    Date published: 2017-02-28
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    Rated 5 out of 5 by from Great Western blot data of DMGDH expressionGreat Western blot data of DMGDH expression in human liver and rat liver tissue extracts. -SCBT QC
    Date published: 2013-09-12
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    DMGDH Antibody (A-9) is rated 5.0 out of 5 by 1.
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