BCOR Antibody Summary
| Immunogen |
Peptide with sequence LSATPLYGNVHSW-C corresponding to N-Terminus according to NP_060215.4, NP_001116855.1, NP_001116856.1, NP_001116857.1. |
| Specificity |
This antibody is expected to recognise all reported isoforms. Variants (NP_060215.4; NP_001116855.1) encode the same isoform. |
| Isotype |
IgG |
| Clonality |
Polyclonal |
| Host |
Goat |
| Gene |
BCOR |
| Purity |
Immunogen affinity purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- Immunocytochemistry/ Immunofluorescence
- Peptide ELISA Detection limit 1:28000
|
| Control |
|
Reactivity Notes
Expected from sequence similarity: Mouse, Dog, Pig, Cow
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles. |
| Buffer |
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA |
| Preservative |
0.02% Sodium Azide |
| Concentration |
0.5 mg/ml |
| Purity |
Immunogen affinity purified |
Alternate Names for BCOR Antibody
Background
BCOR is encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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Video Protocols
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Control Lysate(s)
Secondary Antibodies
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Isotype Controls
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![Immunofluorescence: BCOR Antibody [NB100-1280] - Analysis of paraformaldehyde fixed A431 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing nuclear and weak cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).](http://images.novusbio.com/fullsize/BCOR-Antibody-Immunofluorescence-NB100-1280-img0002.jpg "Immunofluorescence: BCOR Antibody [NB100-1280] - Analysis of paraformaldehyde fixed A431 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing nuclear and weak cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).")
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