ALDH1A1 Antibody (A-6) is a mouse monoclonal IgG1 antibody that detects aldehyde dehydrogenase 1A1 (ALDH1A1) in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ALDH1A1 plays a crucial role in the biosynthesis of retinoic acid, a vital signaling molecule involved in numerous biological processes such as embryonic development, cell differentiation, and immune function. ALDH1A1 catalyzes the conversion of retinaldehyde to retinoic acid, which is essential for regulating gene expression and maintaining cellular homeostasis. Notably, alterations in retinoic acid levels have been implicated in various diseases, including cancer, where dysregulation of ALDH1A1 expression can contribute to tumor progression and resistance to chemotherapy. ALDH1A1 localization in the cytosol and mitochondria underscores its importance in metabolic pathways, efficiently detoxifying aldehydes and protecting cells from oxidative stress. With significant roles in retinoic acid synthesis and cellular detoxification, anti-ALDH1A1 antibody (A-6) serves as an invaluable tool for researchers studying metabolic processes and their implications in health and disease.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Aldehyde dehydrogenase 1-A1/ALDH1A1 Antibody (A-6) | sc-398578 | 200 µg/ml | $316.00 | |||
Aldehyde dehydrogenase 1-A1/ALDH1A1 Antibody (A-6): m-IgG Fc BP-HRP Bundle | sc-538474 | 200 µg Ab; 10 µg BP | $354.00 | |||
Aldehyde dehydrogenase 1-A1/ALDH1A1 Antibody (A-6): m-IgGκ BP-HRP Bundle | sc-536096 | 200 µg Ab; 40 µg BP | $354.00 | |||
Aldehyde dehydrogenase 1-A1/ALDH1A1 Antibody (A-6): m-IgG1 BP-HRP Bundle | sc-545719 | 200 µg Ab; 20 µg BP | $354.00 | |||
Aldehyde dehydrogenase 1-A1/ALDH1A1 (A-6) Neutralizing Peptide | sc-398578 P | 100 µg/0.5 ml | $68.00 |