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SLA2 Antibody (5-RE27) is a mouse monoclonal IgG1 antibody that detects SLA2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). SLA2, also known as Src-like-adapter 2 or C20orf156, is a 261 amino acid protein that plays a crucial role as an adaptor protein in the immune system, primarily expressed in the thymus, spleen, and lymph nodes. SLA2 is essential for regulating T-cell receptor (TCR) signaling, as SLA2 negatively modulates T-cell activation, thereby influencing immune responses. Notably, SLA2 interacts with Zap-70, a key player in T-cell signaling pathways, and undergoes post-translational modifications such as phosphorylation, which can affect function and interactions. The gene encoding SLA2 is located on human chromosome 20, a chromosome that comprises approximately 2% of the human genome and contains over 600 genes, some of which are implicated in various diseases, including Creutzfeldt-Jakob disease and amyotrophic lateral sclerosis. SLA2 (5-RE27) antibody is an invaluable tool for researchers studying T-cell signaling and immune regulation, providing insights into the complex mechanisms that govern immune responses.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SLA2 Antibody (5-RE27) | sc-135561 | 100 µg/ml | $333.00 |