Mast Cell Chymase Antibody (2Q1506): sc-71540
- Mast Cell Chymase Antibody (2Q1506) is a mouse monoclonal IgG1 provided at 200 µg/ml
- raised against purified skin chymase of human origin
- recommended for detection of Mast Cell Chymase distributed in skin, synovium, lung and heart of mouse, rat and human origin by WB, IF and IHC(P); also reactive with additional species, including and porcine and canine
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Mast Cell Chymase Antibody (2Q1506). This work is in progress.
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Mast Cell Chymase Antibody (2Q1506) is a mouse monoclonal IgG1 antibody that detects Mast Cell Chymase in mouse, rat, and human samples through applications such as western blotting (WB), immunofluorescence (IF), and immunohistochemistry. Mast Cell Chymase (CMA1/MCT1) is a crucial serine protease secreted by mast cells, playing a significant role in the generation of vasoactive peptides, degradation of the extracellular matrix, and regulation of gland secretion. Mast Cell Chymase is primarily located in mast cells, where anti-Mast Cell Chymase antibody (2Q1506) can detect contributions to inflammatory and immune responses through modulation of the extracellular environment and tissue remodeling. The human chymase gene, located on chromosome 14q11.2, encodes a preproenzyme that includes a 19 amino acid signal peptide, an acidic 2 amino acid propeptide, and a 226 amino acid catalytic domain, highlighting its complex structure and functional importance. Mast Cell Chymase is classified as a chymotryptic serine proteinase and belongs to the peptidase family S1, underscoring its enzymatic activity in processing various substrates. Additionally, mast cell proteases, which are homologous to human tryptases, serve as specific markers for analyzing mast cell heterogeneity, differentiation, and function, making Mast Cell Chymase (2Q1506) monoclonal antibody an invaluable tool for researchers studying mast cell biology and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Mast Cell Chymase Antibody (2Q1506) | sc-71540 | 200 µg/ml | $316.00 |