Enolase Antibody (B-8) is a mouse monoclonal IgM antibody that detects Enolase in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Enolase is a crucial enzyme in the glycolytic pathway, facilitating the conversion of 2-phosphoglycerate to phosphoenolpyruvate, a key step in energy production. This process is vital for cellular metabolism, particularly in tissues with high energy demands, such as muscle and brain. The enzyme exists in three isoforms—α, β, and γ—each with distinct tissue distribution and functional roles, highlighting the importance of enolase in various physiological contexts. Notably, α Enolase is expressed widely across tissues, while β Enolase is predominantly found in muscle, and γ Enolase is specific to nervous tissue. Enolase consists of 433 amino acids and exhibits significant evolutionary conservation, showing 67% homology to yeast enolase and 94% homology to rat nonneural enolase. Additionally, α Enolase is encoded by the same gene as tau-crystallin, a structural protein in the lens, underscoring its multifaceted roles in both metabolic and structural functions within cells. Anti-Enolase antibody (B-8) is an essential tool for researchers studying glycolysis and its implications in various biological processes and diseases.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Enolase Antibody (B-8) | sc-271792 | 200 µg/ml | $316.00 | |||
Enolase (B-8) Neutralizing Peptide | sc-271792 P | 100 µg/0.5 ml | $68.00 |