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PIK3R2 / p85 Beta
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Indirectly regulates autophagy (PubMed:23604317).
| Gene Name: | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| Family/Subfamily: | Non-Protein Kinase , not assigned-Non-Protein Kinase |
| Synonyms: | PIK3R2, p85, p85B, p85-BETA, PI3K regulatory subunit beta, MPPH, PI3-kinase subunit p85-beta |
| Target Sequences: | NM_005027 NP_005018.1 O00459 |
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PIK3R2 / p85 Beta
(59)
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(55)
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(17)
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(9)
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(49)
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(1)
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(2)
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(2)
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PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa447-461) Antibody
Mouse, Guinea pig, Sheep, Bovine, Rat, Pig, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µg/$470
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (Tyr467) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$375
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (Tyr467) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (Tyr467) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (Tyr467) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (Tyr467) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (Tyr467) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (Tyr467) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa268-298) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa268-298) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa268-298) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa268-298) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa268-298) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa268-298) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa268-298) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (pTyr464) Antibody
Mouse, Rat, Human
ELISA, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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