Blood Group B antigen Antibody (89-F): sc-52371

Blood Group B antigen Antibody (89-F) is a mouse monoclonal IgM antibody that detects Blood Group B antigen of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Blood Group B antigen (89-F) antibody is available in non-conjugated form. Blood Group B antigen plays a crucial role in immune response and blood transfusion compatibility, as it is one of the key determinants of blood type in humans. Blood Group B antigen is primarily located on the surface of erythrocytes and certain epithelial cells, where Blood Group B antigen contributes to cell-cell recognition and signaling processes. Understanding Blood Group B antigen distribution is vital, especially in clinical settings, as Blood Group B antigen can influence transfusion reactions and organ transplant compatibility. Additionally, Blood Group B antigen presence can be modulated during malignant transformations, making Blood Group B antigen a significant marker in cancer research. The complexity of blood group antigens, including interrelated specificities such as A, H, and Lewis antigens, highlights Blood Group B antigen importance in both health and disease, providing valuable insights for diagnostics and therapeutic interventions.

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Blood Group B antigen Antibody (89-F) References:

1. Isolation of a B-specific disaccharide from human blood-group B substance.  |  PAINTER, TJ., et al. 1962. Nature. 193: 1042-4. PMID: 14483250
2. Loss of blood-group-B antigen in chronic lymphatic leukaemia.  |  RICHARDS, AG. 1962. Lancet. 2: 178-9. PMID: 14491924
3. Bifidobacterial α-galactosidase with unique carbohydrate-binding module specifically acts on blood group B antigen.  |  Wakinaka, T., et al. 2013. Glycobiology. 23: 232-40. PMID: 23089618
4. The B antigen protects against the development of red meat allergy.  |  Brestoff, JR., et al. 2018. J Allergy Clin Immunol Pract. 6: 1790-1791.e3. PMID: 29510233
5. Differential enzymatic deglycosylation reveals attachment of red cell B antigen onto the carbohydrate moiety of glycophorin A and glycophorin B.  |  Hsu, K. 2023. Vox Sang. 118: 147-152. PMID: 36510386
6. Suppressed expression of blood group B antigen and blood group galactosyltransferase in a preleukemic subject.  |  Yoshida, A., et al. 1985. Blood. 66: 990-2. PMID: 3929862
7. Normal blood group B antigen and B transferase activity in a patient with IgM autoanti-B agglutinin.  |  Lopez, M., et al. 1978. Vox Sang. 34: 18-21. PMID: 414449
8. Hepatitis B antigen and antibody in blood donors: an epidemiologic study.  |  Szmuness, W., et al. 1973. J Infect Dis. 127: 17-25. PMID: 4630236
9. Expression of a blood group B antigen-related glycoepitope in human dorsal root ganglion cells.  |  Yamada, M., et al. 1994. J Neurol Sci. 126: 178-83. PMID: 7531759
10. A combined approach for quantitation of each specific HLA-A or -B antigen expressed on cells.  |  Shieh, DC. and Kao, KJ. 1995. J Immunol Methods. 184: 169-76. PMID: 7658021

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Blood Group B antigen Antibody (89-F) has 2 citations in a variety of scientific publications.

Primary antibodies like Anti-Blood Group B antigen Antibody (89-F) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Blood Group B antigen Antibody (89-F) Specifications

Alternate Product Name: Blood Group B antigen

Product Clone Name: 89-F

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM

Amino Acids:

Epitope Target: Blood Group B antigen

Epitope Species: human

Product Reactivity/Detection: Blood Group B antigen

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, FCM

Vialing Information: Each vial contains 100 µg IgM in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 2 citations in various scientific publications

Available Conjugates/Forms for Blood Group B antigen Antibody (89-F): N/A

The preferred Blood Group B Antigen antibody is Blood Group B Antigen Antibody (Z5H-2): sc-69952.