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Notch Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Notch Antibodies for research focused on understanding the Notch signaling pathway. Notch Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The Notch signaling pathway plays a critical role in cell differentiation, proliferation, and apoptosis, making it essential for proper development and tissue homeostasis. Dysregulation of Notch signaling has been implicated in various diseases, including cancer and developmental disorders, highlighting the importance of studying this pathway. Notch pathway research has revealed significant insights into cellular communication and development processes. Understanding Notch signaling mechanisms has become increasingly important in developing therapeutic strategies for various pathological conditions. Recent advances in Notch research have uncovered new regulatory mechanisms and potential therapeutic targets. Investigating Notch proteins has led to breakthroughs in understanding tissue regeneration and stem cell biology. Santa Cruz Biotechnology monoclonal antibodies for Notch research support scientists worldwide in advancing our understanding of cellular signaling and disease mechanisms.

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Notch Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Notch1 Antibody (A-8)

sc-376403mouse IgM κ2415-2453 (h)WB, IP, IF, IHC(P), ELISAm, r, h
50
(27)

Notch1 Antibody (mN1A)

sc-32745mouse IgG1 κ(m)WB, IPm, r, h
27
(13)

Notch1 Antibody (C-10)

sc-373891mouse IgG2b κ2433-2467 (h)WB, IP, IF, ELISAm, r, h
26
(7)

Notch1 Antibody (8G10)

sc-32756S. hamster IgG1299-1492 (m)WB, IP, IFm, r
8
(2)

Notch1 Antibody (E-4)

sc-373944mouse IgG2b κC-Terminal (h)WB, IP, IF, ELISAm, r, h
4
(3)

Notch1 Antibody (4i50)

sc-71719S. hamster IgG1299-1492 (m)WB, IP, IFm, r
4
(1)

Notch 2 Antibody (C-2)

sc-518049mouse IgM κ2442-2471 (m)WB, IP, IF, ELISAm, r
1
(1)

Notch 2 Antibody (F-10)

sc-518169mouse IgM κ248-272 (h)WB, IP, IF, ELISAh
2
(2)

Notch 3 Antibody (A-6)

sc-515825mouse IgM κ2290-2316 (m)WB, IP, IF, ELISAm, r, h
7
(6)

Notch 4 Antibody (A-12)

sc-393893mouse IgG2a κ1933-1964 (m)WB, IP, IF, ELISAm, r, h
10
(6)

Notch 4 Antibody (C-3)

sc-377399mouse IgG3 κ3-31 (m)WB, IP, IF, IHC(P), ELISAm, r
2
(2)

Notch CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Notch1 CRISPR/Cas9 KO Plasmid (h2)

sc-400167-KO-2hGene KnockoutGFP0
(0)

Notch1 HDR Plasmid (h2)

sc-400167-HDR-2hHomology Directed RepairPuromycin0
(0)

Notch1 Double Nickase Plasmid (h)

sc-400167-NIChGene KnockoutPuromycin0
(0)

Notch1 Double Nickase Plasmid (h2)

sc-400167-NIC-2hGene KnockoutPuromycin0
(0)

Notch1 CRISPR/Cas9 KO Plasmid (m2)

sc-421930-KO-2mGene KnockoutGFP0
(0)

Notch1 Double Nickase Plasmid (m)

sc-421930-NICmGene KnockoutPuromycin0
(0)

Notch1 Double Nickase Plasmid (m2)

sc-421930-NIC-2mGene KnockoutPuromycin0
(0)

Notch 2 CRISPR/Cas9 KO Plasmid (h2)

sc-401323-KO-2hGene KnockoutGFP0
(0)

Notch 2 HDR Plasmid (h2)

sc-401323-HDR-2hHomology Directed RepairPuromycin0
(0)

Notch 2 Double Nickase Plasmid (h)

sc-401323-NIChGene KnockoutPuromycin0
(0)

Notch 2 Double Nickase Plasmid (h2)

sc-401323-NIC-2hGene KnockoutPuromycin0
(0)

Notch 2 CRISPR/Cas9 KO Plasmid (m)

sc-421931mGene KnockoutGFP0
(0)

Notch 2 HDR Plasmid (m)

sc-421931-HDRmHomology Directed RepairPuromycin0
(0)

Notch 2 Double Nickase Plasmid (m)

sc-421931-NICmGene KnockoutPuromycin0
(0)

Notch 2 Double Nickase Plasmid (m2)

sc-421931-NIC-2mGene KnockoutPuromycin0
(0)

Notch 3 CRISPR/Cas9 KO Plasmid (h)

sc-400424hGene KnockoutGFP0
(0)

Notch 3 HDR Plasmid (h)

sc-400424-HDRhHomology Directed RepairPuromycin0
(0)

Notch 3 Double Nickase Plasmid (h)

sc-400424-NIChGene KnockoutPuromycin0
(0)

Notch 3 Double Nickase Plasmid (h2)

sc-400424-NIC-2hGene KnockoutPuromycin0
(0)

Notch 3 CRISPR/Cas9 KO Plasmid (m)

sc-421933mGene KnockoutGFP0
(0)

Notch 3 Double Nickase Plasmid (m)

sc-421933-NICmGene KnockoutPuromycin0
(0)

Notch 3 Double Nickase Plasmid (m2)

sc-421933-NIC-2mGene KnockoutPuromycin0
(0)

Notch 4 CRISPR/Cas9 KO Plasmid (h)

sc-400766hGene KnockoutGFP0
(0)

Notch 4 HDR Plasmid (h)

sc-400766-HDRhHomology Directed RepairPuromycin0
(0)

Notch 4 Double Nickase Plasmid (h)

sc-400766-NIChGene KnockoutPuromycin0
(0)

Notch 4 Double Nickase Plasmid (h2)

sc-400766-NIC-2hGene KnockoutPuromycin0
(0)

Notch 4 CRISPR/Cas9 KO Plasmid (m)

sc-421934mGene KnockoutGFP0
(0)

Notch 4 Double Nickase Plasmid (m)

sc-421934-NICmGene KnockoutPuromycin0
(0)

Notch 4 Double Nickase Plasmid (m2)

sc-421934-NIC-2mGene KnockoutPuromycin0
(0)

Notch CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Notch1 CRISPR Activation Plasmid (h)

sc-400167-ACThGene ActivationPuro, Blast, Hygro0
(0)

Notch1 CRISPR Activation Plasmid (h2)

sc-400167-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Notch1 Lentiviral Activation Particles (h)

sc-400167-LAChGene ActivationPuro, Blast, Hygro0
(0)

Notch1 Lentiviral Activation Particles (h2)

sc-400167-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Notch1 CRISPR Activation Plasmid (m)

sc-421930-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Notch1 CRISPR Activation Plasmid (m2)

sc-421930-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Notch1 Lentiviral Activation Particles (m)

sc-421930-LACmGene ActivationPuro, Blast, Hygro0
(0)

Notch1 Lentiviral Activation Particles (m2)

sc-421930-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Notch 2 CRISPR Activation Plasmid (h)

sc-401323-ACThGene ActivationPuro, Blast, Hygro0
(0)

Notch 2 CRISPR Activation Plasmid (h2)

sc-401323-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Notch 2 Lentiviral Activation Particles (h)

sc-401323-LAChGene ActivationPuro, Blast, Hygro0
(0)

Notch 2 Lentiviral Activation Particles (h2)

sc-401323-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Notch 2 CRISPR Activation Plasmid (m)

sc-421931-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Notch 2 CRISPR Activation Plasmid (m2)

sc-421931-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Notch 2 Lentiviral Activation Particles (m)

sc-421931-LACmGene ActivationPuro, Blast, Hygro0
(0)

Notch 2 Lentiviral Activation Particles (m2)

sc-421931-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Notch 3 CRISPR Activation Plasmid (h)

sc-400424-ACThGene ActivationPuro, Blast, Hygro0
(0)

Notch 3 CRISPR Activation Plasmid (h2)

sc-400424-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Notch 3 Lentiviral Activation Particles (h)

sc-400424-LAChGene ActivationPuro, Blast, Hygro0
(0)

Notch 3 Lentiviral Activation Particles (h2)

sc-400424-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Notch 3 CRISPR Activation Plasmid (m)

sc-421933-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Notch 3 CRISPR Activation Plasmid (m2)

sc-421933-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Notch 3 Lentiviral Activation Particles (m)

sc-421933-LACmGene ActivationPuro, Blast, Hygro0
(0)

Notch 3 Lentiviral Activation Particles (m2)

sc-421933-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Notch 4 CRISPR Activation Plasmid (h)

sc-400766-ACThGene ActivationPuro, Blast, Hygro0
(0)

Notch 4 CRISPR Activation Plasmid (h2)

sc-400766-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Notch 4 Lentiviral Activation Particles (h)

sc-400766-LAChGene ActivationPuro, Blast, Hygro0
(0)

Notch 4 Lentiviral Activation Particles (h2)

sc-400766-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Notch 4 CRISPR Activation Plasmid (m)

sc-421934-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Notch 4 CRISPR Activation Plasmid (m2)

sc-421934-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Notch 4 Lentiviral Activation Particles (m)

sc-421934-LACmGene ActivationPuro, Blast, Hygro0
(0)

Notch 4 Lentiviral Activation Particles (m2)

sc-421934-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Notch siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Notch1 siRNA (h)

sc-36095hGene SilencingN/A
84
(0)

Notch1 siRNA (h2)

sc-44226hGene SilencingN/A
9
(0)

Notch1 shRNA Plasmid (h)

sc-36095-SHhGene SilencingPuromycin
84
(0)

Notch1 shRNA Plasmid (h2)

sc-44226-SHhGene SilencingPuromycin
9
(0)

Notch1 shRNA (h) Lentiviral Particles

sc-36095-VhGene SilencingPuromycin
84
(0)

Notch1 shRNA (h2) Lentiviral Particles

sc-44226-VhGene SilencingPuromycin
9
(0)

Notch1 siRNA (m)

sc-36096mGene SilencingN/A
7
(0)

Notch1 siRNA (m2)

sc-44315mGene SilencingN/A0
(0)

Notch1 shRNA Plasmid (m)

sc-36096-SHmGene SilencingPuromycin
7
(0)

Notch1 shRNA Plasmid (m2)

sc-44315-SHmGene SilencingPuromycin0
(0)

Notch1 shRNA (m) Lentiviral Particles

sc-36096-VmGene SilencingPuromycin
7
(0)

Notch1 shRNA (m2) Lentiviral Particles

sc-44315-VmGene SilencingPuromycin0
(0)

Notch1 siRNA (r)

sc-270189rGene SilencingN/A
12
(0)

Notch1 shRNA Plasmid (r)

sc-270189-SHrGene SilencingPuromycin
12
(0)

Notch1 shRNA (r) Lentiviral Particles

sc-270189-VrGene SilencingPuromycin
12
(0)

Notch 2 siRNA (h)

sc-40135hGene SilencingN/A
24
(0)

Notch 2 shRNA Plasmid (h)

sc-40135-SHhGene SilencingPuromycin
24
(0)

Notch 2 shRNA (h) Lentiviral Particles

sc-40135-VhGene SilencingPuromycin
24
(0)

Notch 2 siRNA (m)

sc-40136mGene SilencingN/A
3
(0)

Notch 2 shRNA Plasmid (m)

sc-40136-SHmGene SilencingPuromycin
3
(0)

Notch 2 shRNA (m) Lentiviral Particles

sc-40136-VmGene SilencingPuromycin
3
(0)

Notch 3 siRNA (h)

sc-37135hGene SilencingN/A
14
(0)

Notch 3 shRNA Plasmid (h)

sc-37135-SHhGene SilencingPuromycin
14
(0)

Notch 3 shRNA (h) Lentiviral Particles

sc-37135-VhGene SilencingPuromycin
14
(0)

Notch 3 siRNA (m)

sc-37136mGene SilencingN/A
6
(0)

Notch 3 shRNA Plasmid (m)

sc-37136-SHmGene SilencingPuromycin
6
(0)

Notch 3 shRNA (m) Lentiviral Particles

sc-37136-VmGene SilencingPuromycin
6
(0)

Notch 4 siRNA (h)

sc-40137hGene SilencingN/A
10
(0)

Notch 4 shRNA Plasmid (h)

sc-40137-SHhGene SilencingPuromycin
10
(0)

Notch 4 shRNA (h) Lentiviral Particles

sc-40137-VhGene SilencingPuromycin
10
(0)

Notch 4 siRNA (m)

sc-40138mGene SilencingN/A
1
(0)

Notch 4 shRNA Plasmid (m)

sc-40138-SHmGene SilencingPuromycin
1
(0)

Notch 4 shRNA (m) Lentiviral Particles

sc-40138-VmGene SilencingPuromycin
1
(0)