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Transcriptional regulator that binds to the GA element of the CLCNKA promoter. Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart By similarity. Is a repressor of CTGF expression, involved in the control of cardiac fibrosis. It is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A and GATA4 By similarity. Involved in podocyte differentiation By similarity. Inhibits MYOCD activity. Is a negative regulator of TP53 acetylation. Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation.
Gene Name: | Kruppel-like factor 15 |
Synonyms: | KLF15, Krueppel-like factor 15, KKLF, Kruppel-like factor 15 |
Target Sequences: | NM_014079 NP_054798.1 Q9UIH9 |
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