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BAF60B / SMARCD2 is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Name: | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 |
Synonyms: | SMARCD2, BAF60B, BRG1-associated factor 60B, CRACD2, PRO2451, Rsc6p, Swp73-like protein, Swi/snf complex 60 kda subunit |
Target Sequences: | NM_003077 NP_003068.3 Q92925 |
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