Rpp38 Antibody (B-6): sc-398113
- Rpp38 Antibody (B-6) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 205-246 mapping near the C-terminus of Rpp38 of human origin
- recommended for detection of Rpp38 of human origin by WB, IP, IF and ELISA
- m-IgG2b BP-HRP is the preferred secondary detection reagent for Rpp38 Antibody (B-6) for WB applications. This reagent is now offered in a bundle with Rpp38 Antibody (B-6) (see ordering information below).
QUICK LINKS
Rpp38 Antibody (B-6) is a mouse monoclonal IgG2b antibody that detects Rpp38 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Rpp38 is a crucial component of the ribonuclease P complex, which is essential for the maturation of precursor tRNA molecules by removing their 5-prime leader sequences, thereby facilitating proper protein synthesis. Rpp38 is predominantly localized in the nucleolus, where Rpp38 plays a vital role in the processing of RNA substrates, including the formation of the mature 5′ end of tRNA. The nucleolar localization of Rpp38 underscores Rpp38′s involvement in the regulation of gene expression and RNA processing, which are critical for cellular function and homeostasis. Additionally, Rpp38 is associated with Th/To ribonucleoproteins, and Rpp38′s interaction with other proteins in the complex has been linked to autoimmune diseases, such as systemic sclerosis, highlighting Rpp38′s importance not only in normal cellular processes but also in disease mechanisms. anti-Rpp38 antibody (B-6) provides a valuable tool for researchers studying RNA processing and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rpp38 Antibody (B-6) | sc-398113 | 200 µg/ml | $316.00 | |||
Rpp38 Antibody (B-6): m-IgG2b BP-HRP Bundle | sc-548626 | 200 µg Ab; 10 µg BP | $354.00 |