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ITF-2 Antibody (367.2) is a mouse monoclonal IgG1 antibody that detects immunoglobulin transcription factor 2 (ITF-2) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). ITF-2 plays a crucial role in the regulation of gene expression, particularly in muscle development, by binding to specific DNA motifs such as the immunoglobulin enhancer Mu-E5/KE5-motif and the Ephrussi-box (E-box) element found in SSTR2-INR. Anti-ITF-2 antibody (367.2) recognizes a transcription factor essential for activating muscle-specific genes, with the ability to form homo- or hetero-oligomers with other myogenic factors like myogenin and MyoD. ITF-2 expression in various tissues, including the adult heart, brain, placenta, and skeletal muscle, highlights a ubiquitous role in cellular processes. Additionally, alternatively spliced isoforms of ITF-2 allow for nuanced regulation of transcription, enabling either activation or repression of target genes, which is vital for maintaining proper muscle function and development. ITF-2 monoclonal antibody (367.2) serves as an invaluable tool for researchers studying muscle biology and transcriptional regulation.
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Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ITF-2/TCF4 Antibody (367.2) | sc-101095 | 100 µg/ml | $333.00 |