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CBP/KAT3A/CREBBP Antibody (F-4): sc-271974

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Datasheets
  • CBP/KAT3A/CREBBP Antibody (F-4) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against a sequence mapping within the CREB Binding Domain of CBP of mouse origin
  • recommended for detection of CBP p265 and p300 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
  • TransCruz reagent for Gel Supershift and ChIP applications (sc-271974 X, 200 µg/0.1 ml)
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CBP/KAT3A/CREBBP Antibody (F-4) for WB and IHC(P) applications. These reagents are now offered in bundles with CBP/KAT3A/CREBBP Antibody (F-4) (see ordering information below).

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    CBP Antibody (F-4) is a mouse monoclonal IgG1 antibody that detects CBP in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). CREB-binding protein (CBP) plays a crucial role in gene expression regulation by acting as a co-activator for numerous transcription factors, particularly those activated by cyclic AMP signaling. CBP is primarily located in the nucleus, where CBP interacts with transcription factors like CREB, facilitating the transcription of target genes essential for processes such as cell growth, differentiation, and response to hormonal signals. CBP′s nuclear localization enables precise regulation of gene expression in response to various stimuli, thereby influencing cellular functions and maintaining homeostasis. CBP undergoes post-translational modifications, including acetylation and phosphorylation, which can further modulate CBP′s activity and interactions with other proteins, underscoring CBP′s significance in cellular signaling pathways. Anti-CBP antibody (F-4) serves as an invaluable tool for researchers studying the intricate mechanisms of gene regulation and the role of co-activators in transcriptional control.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    CBP/KAT3A/CREBBP Antibody (F-4)

    sc-271974
    200 µg/ml
    $316.00

    CBP/KAT3A/CREBBP Antibody (F-4): m-IgG Fc BP-HRP Bundle

    sc-537715
    200 µg Ab; 10 µg BP
    $354.00

    CBP/KAT3A/CREBBP Antibody (F-4): m-IgGκ BP-HRP Bundle

    sc-535076
    200 µg Ab; 40 µg BP
    $354.00

    CBP/KAT3A/CREBBP Antibody (F-4): m-IgG1 BP-HRP Bundle

    sc-545324
    200 µg Ab; 20 µg BP
    $354.00

    CBP/KAT3A/CREBBP Antibody (F-4) X

    sc-271974 X
    200 µg/0.1 ml
    $316.00

    Can CBP (F-4): sc-271974 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: DefinitelyNotMatt
    Thank you for your question. Yes, CBP (F-4): sc-271974 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-02-27
    • y_2025, m_4, d_8, h_5CST
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    • QUESTIONS, PRODUCT
    Rated 3 out of 5 by from Nuclei from mouse brainNuclei from mouse brain. Band above the 200 kDa. Other lower molecular weight bands (likely to be CBP cleavage products) are also visible.
    Date published: 2015-08-21
    Rated 5 out of 5 by from Produced excellent immunofluorescence nuclearProduced excellent immunofluorescence nuclear staining in methanol-fixed HeLa cells. -SCBT QC
    Date published: 2015-04-14
    Rated 3 out of 5 by from Positive result in WB using HeLa and JurkatPositive result in WB using HeLa and Jurkat nuclear extracts. -SCBT QC
    Date published: 2015-03-30
    Rated 3 out of 5 by from Positive result seen in WB using KNRK and 3611Positive result seen in WB using KNRK and 3611-RF nuclear extracts. -SCBT QC
    Date published: 2015-01-24
    • y_2025, m_4, d_8, h_5
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    CBP/KAT3A/CREBBP Antibody (F-4) is rated 3.5 out of 5 by 4.
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