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CBP80 Antibody (G-4) is a mouse monoclonal IgG1 antibody that detects CBP80 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CBP80 plays a crucial role in mRNA metabolism, particularly in nonsense-mediated decay (NMD), which maintains gene expression integrity by eliminating mRNAs that prematurely terminate translation. This function ensures that only properly processed and full-length mRNAs are translated into proteins, preventing the production of truncated and potentially harmful proteins. CBP80 forms part of the cap-binding complex with CBP20, facilitating critical processes such as pre-mRNA splicing and 3′ end formation. CBP80′s structure, comprising three domains each containing a MIF4G domain, enables effective interaction with CBP20, enhancing binding to the m(7)G cap of mRNAs. Anti-CBP80 antibody (G-4) helps researchers gain insights into mRNA processing dynamics and gene expression regulation, making CBP80 (G-4) monoclonal antibody an invaluable tool for molecular biology and genetics studies.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CBP80 Antibody (G-4) | sc-271305 | 200 µg/ml | $316.00 | |||
CBP80 Antibody (G-4): m-IgG Fc BP-HRP Bundle | sc-537606 | 200 µg Ab; 10 µg BP | $354.00 | |||
CBP80 Antibody (G-4): m-IgGκ BP-HRP Bundle | sc-534921 | 200 µg Ab; 40 µg BP | $354.00 | |||
CBP80 Antibody (G-4): m-IgG1 BP-HRP Bundle | sc-545257 | 200 µg Ab; 20 µg BP | $354.00 | |||
CBP80 Antibody (G-4) X | sc-271305 X | 200 µg/0.1 ml | $316.00 |