p-ATF-2 Antibody (103C411) is a mouse monoclonal IgG1 antibody that detects p-ATF-2 in human samples through western blotting (WB). p-ATF-2, a phosphorylated form of ATF-2, plays a crucial role in regulating gene transcription, particularly in response to stress signals. p-ATF-2 is primarily located in the nucleus, where p-ATF-2 functions as a transcription factor binding to specific DNA sequences to modulate target gene expression. Nuclear localization of p-ATF-2 enables interaction with other transcription factors and co-regulators, influencing cellular processes like survival, differentiation, and apoptosis. p-ATF-2 regulates genes managing oxidative stress and inflammation, making p-ATF-2 vital for cellular homeostasis. Located on chromosome 2q31.1, human p-ATF-2 is critical for transcriptional response to environmental stimuli, highlighting p-ATF-2′s importance in normal physiology and disease states.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-ATF-2 Antibody (103C411) | sc-52941 | 100 µg/ml | $316.00 |