Recombinant Human TSG-6 Protein, CF

Name Recombinant Human TSG-6 Protein, CF
Supplier R&D Systems
Catalog 2104-TS
Category Protein
Prices $329.00
Sizes 50 µg
Species Reactivities Human
Nature Recombinant
Source Mouse myeloma cell line, NS0-derived Trp18-Leu277, with a C-terminal 10-His tag
Purity >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Bioactivity Measured by its binding ability in a functional ELISA. When Recombinant Human TSG-6 is present at 0.5 μg/well, the concentration of biotinylated hyaluronan that produces 50% of the optimal binding response is found to be approximately 4-30 ng/mL.
Endotoxin <0.10 EU per 1 μg of the protein by the LAL method.
SwissProt/Accession P98066
Gene TNFAIP6
Sequence Trp18
Supplier Page Shop

Product images


Product References

TSG-6 Downregulates IFN-Alpha and TNF-Alpha Expression by Suppressing IRF7 - TSG-6 Downregulates IFN-Alpha and TNF-Alpha Expression by Suppressing IRF7

Kui L, Chan GC, Lee PP. Mediators Inflamm. 2017;2017:7462945.

Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor - Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor

He Z, Hua J, Qian D, Gong J, Lin S, Xu C, Wei G, Meng H, Yang T, Zhou B, Song Z. Sci Rep. 2016 Dec 5;6:38438.

TNFalpha-stimulated gene-6 (TSG6) activates macrophage phenotype transition to - TNFalpha-stimulated gene-6 (TSG6) activates macrophage phenotype transition to

Mittal M, Tiruppathi C, Nepal S, Zhao YY, Grzych D, Soni D, Prockop DJ, Malik AB. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8151-E8158. Epub 2016 Nov 28.

Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with - Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with

Kim DK, Choi H, Nishida H, Oh JY, Gregory C, Lee RH, Yu JM, Watanabe J, An SY, Bartosh TJ, Prockop DJ. PLoS One. 2016 Jan 21;11(1):e0147553.

Hyaluronan and Its Heavy Chain Modification in Asthma Severity and Experimental - Hyaluronan and Its Heavy Chain Modification in Asthma Severity and Experimental

Lauer ME, Majors AK, Comhair S, Ruple LM, Matuska B, Subramanian A, Farver C, Dworski R, Grandon D, Laskowski D, Dweik RA, Erzurum SC, Hascall VC, Aronica MA. J Biol Chem. 2015 Sep 18;290(38):23124-34.

Heavy chain transfer by tumor necrosis factor-stimulated gene 6 to the bikunin - Heavy chain transfer by tumor necrosis factor-stimulated gene 6 to the bikunin

Lamkin E, Cheng G, Calabro A, Hascall VC, Joo EJ, Li L, Linhardt RJ, Lauer ME. J Biol Chem. 2015 Feb 20;290(8):5156-66.

Crucial role of IL1beta and C3a in the in vitro-response of multipotent - Crucial role of IL1beta and C3a in the in vitro-response of multipotent

Hengartner NE, Fiedler J, Schrezenmeier H, Huber-Lang M, Brenner RE. PLoS One. 2015 Jan 6;10(1):e0116772.

Mesenchymal stromal (stem) cells suppress pro-inflammatory cytokine production - Mesenchymal stromal (stem) cells suppress pro-inflammatory cytokine production

Kim H, Darwish I, Monroy MF, Prockop DJ, Liles WC, Kain KC. BMC Immunol. 2014 Jan 14;15:1.

Irreversible heavy chain transfer to hyaluronan oligosaccharides by tumor - Irreversible heavy chain transfer to hyaluronan oligosaccharides by tumor

Lauer ME, Glant TT, Mikecz K, DeAngelis PL, Haller FM, Husni ME, Hascall VC, Calabro A. J Biol Chem. 2013 Jan 4;288(1):205-14.

Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates - Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates

Choi H, Lee RH, Bazhanov N, Oh JY, Prockop DJ. Blood. 2011 Jul 14;118(2):330-8.