Name |
Rat FGF basic
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Supplier |
ABBIOTEC
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Catalog |
600373
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Category |
Protein
|
Prices |
$250.00
|
Sizes |
50 µg
|
Species Reactivities |
Rat
|
Nature |
Recombinant
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Source |
E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
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Purity |
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
|
Bioactivity |
The activity is determined by the dose-dependent proliferation of 3T3 cells and is typically less than 1 ng/mL. Specific activity: 1 x 10e6 units/mg
|
Gene |
Igf1
|
Sequence |
MPALPEDGGG AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH VKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTE ECFFFERLES NNYNTYRSRK YSSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS
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Description |
Fibroblast Growth Factors (FGFs) are a 22 member family of proteins known to be involved in angiogenesis, wound healing and embryonic development. As a family, they bind to heparin and signal through four receptor tyrosine kinases called, FGFR1, 2, 3 and 4. Rat FGF basic is produced in E.coli. Recombinant rat FGF-basic is a non-glycosylated protein, containing 146 amino acids, with a molecular weight of 16.4 kDa.
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