| Name | GH Antagonist Chicken |
|---|---|
| Supplier | NeoScientific |
| Catalog | CYPS-545 |
| Category | Protein |
| Prices | $65.00, $169.00, $1,092.00 |
| Sizes | 20 µg, 100 µg, 1 mg |
| Species Reactivities | Chicken |
| Nature | Recombinant |
| Source | Escherichia Coli. |
| Purity | Greater than 98.0% as determined by:(a) Analysis by SEC-HPLC.(b) Analysis by SDS-PAGE. |
| Bioactivity | Recombinant Chicken Growth Hormone G119R mutant did not bind to ovine GHR-ECD and was devoid of any biological activity in FDC-P1 3B9 cells. However, in binding experiments that were carried out using chicken liver membranes, both ovine GH and chicken GH showed similar IC50 values in competition with 125I-ovine GH, while the IC50 of G119R mutein was 10-fold higher. These results emphasize the importance of species specificity and indicate the possibility of antagonistic activity of chGH G119R in homologous system. |
| Gene | GH |
| Sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Thr-Phe-Pro-Ala. |
| Description | Somatotropin Chicken Antagonist Recombinant mutein G119R produced in E.Coli is a single, non-glycosylated polypeptide chain containing 191 amino acids with an additional Ala at the N-terminus and having a molecular mass of 22.3 kDa. The Chicken Growth-Hormone Antagonist Recombinant is purified by proprietary chromatographic techniques. |
| Supplier Page | Shop |