| Name | Mouse IL-2 protein |
|---|---|
| Supplier | Biorbyt |
| Catalog | orb180537 |
| Category | Protein |
| Prices | $391.00 |
| Sizes | 20 μg |
| Applications | SDS-PAGE HPLC |
| Species Reactivities | Mouse |
| Source | E. coli |
| Purity | > 95.0% |
| Bioactivity | The ED50 range=0.1-0.4 ng/ml ,as determined by the dose-dependant stimulation of murine CTLL-2 cells. |
| Gene | Il2 |
| Sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Pro-Thr-Ser-Ser. |
| Description | IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. |
| Supplier Page | Shop |