| Gene Symbol | och1 |
|---|---|
| Entrez Gene | 2543147 |
| Alt Symbol | - |
| Species | S. pombe |
| Gene Type | protein-coding |
| Description | alpha-1,6-mannosyltransferase Och1 |
| Other Description | - |
| Swissprots | Q9UTR6 |
| Accessions | CAD24818 Q9UTR6 NM_001020281 NP_594852 |
| Function | Mannosyltransferase involved in outer chain elongation of asparagine-linked oligosaccharides of the type Man(9)GlcNAc(2). May otherwise add the first alpha-1,6-mannose to the Man(8)GlNAc(2) core oligosaccharide from the ER. Represents the first enzymatic event required for synthesis of outer chain mannose linkages on yeast secretory proteins. {ECO:0000269|PubMed:11231017, ECO:0000269|PubMed:12784644}. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P31755}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:P31755}. Golgi apparatus membrane {ECO:0000250|UniProtKB:P31755}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:P31755}. Note=Is recycled between the trans-Golgi network and a late compartment of the endoplasmic reticulum. {ECO:0000250|UniProtKB:P31755}. |
| Top Pathways | Various types of N-glycan biosynthesis |