| Gene Symbol | AOC1 |
|---|---|
| Entrez Gene | 26 |
| Alt Symbol | ABP, ABP1, DAO, DAO1, KAO |
| Species | Human |
| Gene Type | protein-coding |
| Description | amine oxidase, copper containing 1 |
| Other Description | amiloride binding protein 1 (amine oxidase (copper-containing))|amiloride-binding protein 1|amiloride-sensitive amine oxidase|amiloride-sensitive amine oxidase [copper-containing]|amine oxidase copper domain-containing protein 1|diamine oxidase|histaminase|kidney amine oxidase |
| Swissprots | Q6GU42 Q16683 P19801 Q16684 Q56II4 C9J690 |
| Accessions | AAX81409 CAA55046 EAL24490 EAW54081 EAW54082 EAW54083 EAW54084 EAW54085 EAW54086 EAW54087 P19801 AK092514 BAG52564 AK296638 BAG59239 AK307278 AK314806 BC014093 AAH14093 BX648159 JF432306 ADZ15523 M55602 AAA58358 U11862 AAC50270 U11863 AAB60381 XM_011516008 XP_011514310 XM_011516009 XP_011514311 NM_001091 NP_001082 NM_001272072 NP_001259001 |
| Function | Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. |
| Subcellular Location | Secreted, extracellular space. |
| Tissue Specificity | Placenta and kidney. |
| Top Pathways | Arginine and proline metabolism, Tryptophan metabolism, Histidine metabolism |