| Gene Symbol | CD1A |
|---|---|
| Entrez Gene | 909 |
| Alt Symbol | CD1, FCB6, HTA1, R4, T6 |
| Species | Human |
| Gene Type | protein-coding |
| Description | CD1a molecule |
| Other Description | CD1A antigen, a polypeptide|T-cell surface antigen T6/Leu-6|T-cell surface glycoprotein CD1a|cluster of differentiation 1 A|cortical thymocyte antigen CD1A|differentiation antigen CD1-alpha-3|epidermal dendritic cell marker CD1a|hTa1 thymocyte antigen |
| Swissprots | P06126 Q13962 D3DVD7 Q9UMM4 Q5TDJ8 Q9Y5M5 |
| Accessions | AAA51932 AAA51934 AAD37578 EAW52843 EAW52844 P06126 AK312945 BAG35786 BC031645 AAH31645 CA432941 DB108750 DQ891346 ABM82272 DQ894526 ABM85452 M27735 AAA51933 M28825 AAA51931 X04450 CAA28049 X79308 X79309 XM_011510117 XP_011508419 XM_011510118 XP_011508420 NM_001763 NP_001754 |
| Function | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. {ECO:0000269|PubMed:11231314, ECO:0000269|PubMed:16272286, ECO:0000269|PubMed:18178838}. |
| Subcellular Location | Cell membrane; Single-pass type I membrane protein. Endosome membrane. Note=Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts. |
| Tissue Specificity | Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues. {ECO:0000269|PubMed:11231314, ECO:0000269|PubMed:18178838}. |
| Top Pathways | Hematopoietic cell lineage |