| Gene Symbol | aop |
|---|---|
| Entrez Gene | 33392 |
| Alt Symbol | AOP, Aop, Aop/Yan, CG3166, DROYANET, DROYANETSB, Dmel\CG3166, SK2-1, YAN, Yan, aop/yan, fus6, pok, yan, yan/pok |
| Species | Drosophila |
| Gene Type | protein-coding |
| Description | anterior open |
| Other Description | CG3166-PA|CG3166-PB|CG3166-PC|CG3166-PD|CG3166-PE|SGP cluster fusion defects 6|anterior-open|aop-PA|aop-PB|aop-PC|aop-PD|aop-PE|pokkuri |
| Swissprots | Q6NR43 Q01842 Q6AWH6 Q9VQ81 |
| Accessions | AAF51297 AAN10445 AGB92445 AGB92446 AGB92447 Q01842 BT015272 AAT94501 NM_001272979 NP_001259908 NM_001272980 NP_001259909 NM_001272981 NP_001259910 NM_078731 NP_523455 NM_164457 NP_722766 |
| Function | Negative regulator of photoreceptor development that acts antagonistically to the proneural signal mediated by RAS. It acts upstream of SINA to inhibit R7 development. {ECO:0000269|PubMed:1495974, ECO:0000269|PubMed:1505027}. |
| Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00237, ECO:0000269|PubMed:1505027}. Note=In undifferentiated cells during the early stages of eye development. |
| Tissue Specificity | Expressed in R7 and cone cells of the eye. {ECO:0000269|PubMed:1505027}. |
| Top Pathways | Dorso-ventral axis formation, MAPK signaling pathway - fly |